L-Norleucine L-正亮氨酸

CAS 327-57-1 MFCD00064423

化学结构图

327-57-1
SMILES: CCCC[C@H](N)C(=O)O

化学属性

Mol. FormulaC6H13NO2
Mol. Weight131.17
Melting Point>300°C
TSCAYes
Density1.038
Solubility1.6 G/100 ML (23 ºC)
Flash Point275 °C
Refractive index23 ° (C=5, 5mol/L HCl)
Boiling Point234.0±23.0 °C at 760 mmHg

别名和识别编码

Chemical NameL-Norleucine
CAS Number327-57-1
Synonym L-Norleucine {LY} L-Norleucine {} {LY} L-Norleucine {} {} {LY} L-Norleucine {} {} {} {LY} L-Norleucine {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Norleucine {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID21236
EC Number206-321-4
Beilstein Registry Number4,432
MDL NumberMFCD00064423
Reaxys-RN1721750
Merck Number6706
Chemical Name TranslationL-正亮氨酸
Wiswesser Line NotationZY4&VQ
LabNetwork Molecule IDLN00238150
InChIInChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
Canonical SMILESN[C@@H](CCCC)C(O)=O
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分类

  • {SNA} Amino Acids, Biochemicals and Reagents, Cell Biology, Chemical Biology, Chemical Synthesis, I - Z, Modified Amino Acids, Norleucine Derivatives, Nutrition Research, Peptide Chemistry, Phytochemicals by Plant (Food/Spice/Herb), Plantago ovata, Unnatural Amino Acid Derivatives
  • Amino Acid Analysis, Amino Acid Standards, Amino Acids, Peptides and Proteins, Analytical Standards, Analytical/Chromatography, Biochemicals and Reagents, Chromatography, Life Sciences Standards, Peptide Analysis and Characterization, Peptides, Standards for Amino Acid Analysis
  • {SNA} Amino Acid Analysis,
  • {SNA} Amino Aci

产品应用

  • A non-essential amino acid. Used as internal standard in amino acid analysis.

相关文献及参考

  • [2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.
  • Internal standard for amino acid analysis: Anal. Biochem., 150, 174 (1985).
  • Merck: 14,6706
  • Merck: 14,6706 Beilstein:4,432
  • Robertson, D., et al.: Toxicol. Sci., 85 (2005),
  • Short: EINECS
  • Short: IV/8A
  • [1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.
  • [1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.
  • [2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xi
RTECSRC6308000
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C {LY} 2-8°C Store at RT. Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 mg/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 8,45,1953

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 12,349,1971

其他信息

  • Alfa Aesar:L-(+)-己氨酸,99% L-(+)-Norleucine, 99%(327-57-1)
  • 储运特性:库房通风低温干燥
  • MSDS 信息:alpha-Aminocaproic acid(327-57-1).msds
  • MOL 文件:327-57-1.mol
  • TCI Shanghai:L-正亮氨酸 L-Norleucine,>;99.0%(T)(327-57-1)
  • 比旋光度:22 ° (c=2, 6N HCl)
  • Acros Organics:L(+)-正亮氨酸 L(+)-Norleucine, 99+%(327-57-1)
  • 图谱信息:L-2-氨基己酸(327-57-1)质谱(MS) L-2-氨基己酸(327-57-1)红外图谱(IR2) L-2-氨基己酸(327-57-1)红外图谱(IR1)
  • 灭火剂:水, 二氧化碳, 干粉, 砂土
  • 海关编码:29224995
  • 类别:有毒物质
  • 升华点:275 °C
  • L-2-氨基己酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xp620022 L-正亮氨酸;L-正白氨酸; L-原亮氨酸; L-原闪白氨基酸; L-2-氨基正己酸 1g/瓶 33.6元 2011/04/16 N0303 L-正亮氨酸 L-Norleucine 100MG 140元 2011/04/16 N0303 L-正亮氨酸 L-Norleucine 1G 458元
  • 可燃性危险特性:可燃;燃烧产生有毒氮氧化物烟雾
  • Sigma Aldrich:327-57-1(sigmaaldrich)

系列性分类


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