Ketoconazole 酮康唑

CAS 65277-42-1 MFCD00058579

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产品品牌/编号/名称 纯度规格 包装 价格和现货
INFI H55638
Ketoconazole 酮康唑
98.0%(LC&T;) 1g ¥ 120
96-99 %
INFI H55638
Ketoconazole 酮康唑
98.0%(LC&T;) 5g ¥ 320
96-99 %
INFI H98013
Ketoconazole 酮康唑
98% 5g ¥ 70
96-99 %
INFI H98013
Ketoconazole 酮康唑
98% 25g ¥ 200
96-99 %
INFI H98013
Ketoconazole 酮康唑
98% 100g ¥ 670
96-99 %
TCI K0045
Ketoconazole
98.0%(LC&T;) 1g ¥ 155
库存 上海市 北京 Tokyo, Japan 天津市
中国国内现货 96-99 %
TCI K0045
Ketoconazole
98.0%(LC&T;) 5g ¥ 396
库存 上海市 北京 Tokyo, Japan 天津市
中国国内现货 96-99 %
J&K 973125
Ketoconazole, 99%
99% 250mg ¥ 60
库存 HB
中国国内现货 96-99 %
J&K 973125
Ketoconazole, 99%
99% 1g ¥ 147
库存 HB
中国国内现货 96-99 %
J&K 973125
Ketoconazole, 99%
99% 5g ¥ 376
库存 HB
中国国内现货 96-99 %
TRC K186000
Ketoconazole
100mg ¥ 630
96-99 %
TRC K186000
Ketoconazole
500mg ¥ 691
96-99 %
TRC K186000
Ketoconazole
1g ¥ 910
96-99 %
TRC K186000
Ketoconazole
2g ¥ 1,540
96-99 %
TRC K186000
Ketoconazole
5g ¥ 2,450
96-99 %
TRC K186000
Ketoconazole
10g ¥ 3,990
96-99 %
Sigma K1003
Ketoconazole
≥98% 100mg ¥ 1,434
库存 SH
中国国内现货 96-99 %
Energy-chemical E020711
Ketoconazole 酮康唑
98% 5g ¥ 55
库存 上海市 北京市
中国国内现货 96-99 %
Energy-chemical E020711
Ketoconazole 酮康唑
98% 25g ¥ 199
库存 上海市 北京市
中国国内现货 96-99 %
Energy-chemical E020711
Ketoconazole 酮康唑
98% 100g ¥ 750
库存 北京市 上海市
中国国内现货 96-99 %
Adamas 74329A
98%+ 5g ¥ 50
库存 上海市 北京
中国国内现货 96-99 %
Adamas 74329B
98%+ 25g ¥ 180
库存 上海市 北京
中国国内现货 96-99 %
Adamas 74329C
98%+ 100g ¥ 970
库存 上海市
中国国内现货 96-99 %
Ark AK139328
98% 1g ¥ 48
库存 上海市 北京
中国国内现货 96-99 %
Ark AK139328
98% 5g ¥ 160
库存 上海市 北京
中国国内现货 96-99 %
Ark AK139328
98% 10g ¥ 304
库存 上海市 北京
中国国内现货 96-99 %
Ark AK139328
98% 25g ¥ 368
库存 上海市 北京
中国国内现货 96-99 %
Ark AK139328
98% 100g ¥ 696
库存 上海市
中国国内现货 96-99 %
Matrix 120008
Ketoconazole
95+% 1g ¥ 936
90+ %
Matrix 120008
Ketoconazole
95+% 5g ¥ 2,808
90+ %
Matrix 120008
Ketoconazole
95+% 10g ¥ 4,680
90+ %
Fluka 1356508
United States Pharmacopeia (USP) Reference Standard 200mg ¥ 4,320
Fluka K0600000
European Pharmacopoeia (EP) Reference Standard 1SAMPLE ¥ 2,135
Acros 45547
Ketoconazole, 98%
1g ¥ 602
96-99 %
Acros 45547
Ketoconazole, 98%
5g ¥ 1,337
96-99 %
Acros 45547
Ketoconazole, 98%
25g ¥ 5,617
96-99 %
Matrix 144331
5g ¥ 7,110
Matrix 144331
25g ¥ 21,314
Aladdin K129737-1g
1g ¥ 35
库存 北京
中国国内现货
Acros 455470010
1g ¥ 581
Acros 455470050
5g ¥ 1,289
Acros 455470250
25g ¥ 5,413
Aladdin K129737-5g
5g ¥ 50
库存 北京
中国国内现货
Aladdin K129737-25g
25g ¥ 198
库存 北京
中国国内现货
Aladdin K129737-100g
100g ¥ 659
库存 北京
中国国内现货
Sigma K1003-100MG
100mg ¥ 1,670
库存 北京
中国国内现货
Key Organics KS-1205
1mg ¥ 220
Key Organics KS-1205
5mg ¥ 262
Key Organics KS-1205
10mg ¥ 336
Key Organics KS-1205
25mg ¥ 546
Key Organics KS-1205
50mg ¥ 777
Key Organics KS-1205
100mg ¥ 1,113
Key Organics AS-12695
5g ¥ 3,780
Key Organics AS-12695
25g ¥ 13,188
Aladdin K129737
Ketoconazole 酮康唑
≥98% 1g ¥ 69
库存 上海市
中国国内现货 96-99 %
Aladdin K129737
Ketoconazole 酮康唑
≥98% 5g ¥ 94
库存 上海市
中国国内现货 96-99 %
Aladdin K129737
Ketoconazole 酮康唑
≥98% 25g ¥ 255
库存 上海市
中国国内现货 96-99 %
Aladdin K129737
Ketoconazole 酮康唑
≥98% 100g ¥ 3,599
库存 上海市
中国国内现货 96-99 %
Key Organic AS-12695
Ketoconazole
>97% 5g ¥ 3,455
96-99 %
Key Organic AS-12695
Ketoconazole
>97% 25g ¥ 12,093
96-99 %
Sigma UC280-5MG
5mg ¥ 2,599
Sigma UC280-10MG
10mg ¥ 4,483
Key Organics DS-6676
25g ¥ 2,589

分类

  • {SNA} Antibiotics A
  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Application Index, Cell Signaling Enzymes, Chemical Structure Class, Core Bioreagents, Imidazoles, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics,

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
Personal Protective Equipment
  • Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSTK7912300
Precautionary statements
  • P201273301+310308+313501
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+310+330
  • P405 Store locked up. 上锁保管。
  • P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. 如果食入:立即呼叫中毒控制中心或医生/医师。
  • P308+313 IF exposed or concerned: Get medical advice/attention. 如接触到或有疑虑:求医/就诊。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
Signal word
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Hazard Codes
  • T,N
Risk Statements
Packing GroupIII
UN Number
  • 2811
Storage condition
  • 0-10
  • 0-10°C
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 23300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   17,373,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 23300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   17,373,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   17,373,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 86 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRUGAY Drugs. International Journal of Current Therapeutics and Applied
   Pharmacology Reviews.  (ADIS Press International Inc., Suite B-30, Oxford
   Ct. Business Center, 582 Middletown Blvd., Langhorne, PA 19047)  V.1- 1971- 
   Volume(issue)/page/year: 23,1,1982

TYPE OF TEST

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 1 umol/L
REFERENCE :
   TUMOAB Tumori.  (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan,
   Italy)  V.1-    1911-  Volume(issue)/page/year: 77,385,1991

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   AMACCQ Antimicrobial Agents and Chemotherapy.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.1-    1972-
   Volume(issue)/page/year: 24,478,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6480 mg/kg
SEX/DURATION            : male 9 week(s) pre-mating
                          female 2 week(s) pre-mating  - 7 day(s) after
                          conception
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 18,1433,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE                    : 1029 mg/kg
SEX/DURATION            : male 60 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - other effects on male
   Endocrine - androgenic
REFERENCE :
   ACENA7 Acta Endocrinologica (Copenhagen).  (Periodica, Skolegade 12 E,
   DK-2500 Valby, Denmark) V.1-    1948-  Volume(issue)/page/year: 110,276,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : male 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(

化学结构图

CAS 65277-42-1  MFCD00058579
SMILES: [3H]C([3H])([3H])C(=O)N1C([3H])([3H])C([3H])([3H])N(C2=C([3H])C([3H])=C(OC([3H])([3H])[C@@]3([3H])O[C@@](OC3([3H])[3H])(C3=C(Cl)C([3H])=C(Cl)C([3H])=C3[3H])C([3H])([3H])N3C([3H])=NC([3H])=C3[3H])C([3H])=C2[3H])C([3H])([3H])C1([3H])[3H] |&1:24,27|

化学属性

Mol. FormulaC26H28Cl2N4O4
Mol. Weight531.43
TSCANo
Melting Point148.0 to 152.0 deg-C

别名和识别编码

Chemical NameKetoconazole
MDL NumberMFCD00058579
CAS Number65277-42-1
Synonym
  • (±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine
  • Ketoderm
  • KW-1414
  • Orifungal M
  • ()-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine
  • Nizoral
  • Panfungol
  • R 41400
  • Ketoconazol
  • (±)-cis-​1-​Acetyl-​4-​(4-​[(2-​[2,4-​dichlorophenyl]​-​2-​[1H-​imidazol-​1-​ylmethyl]​-​1,3-​dioxolan-​4-​yl)​-​methoxy]​phenyl)​piperazine
  • Fungarest
    PubChem Substance ID87560321
    EC Number265-667-4
    Merck Number5302
    Reaxys-RN5488107
    Chemical Name Translation酮康唑
    Beilstein Registry Number5488107
    Wiswesser Line NotationT6N DNTJ AV1 DR DO1- DT5O COTJ BR BG DG& B1- AT5N CNJ
    LabNetwork Molecule IDLN01294533

    系列性分类


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