Artemether Tetrahydrofuran Acetate
CAS 181528-64-3 MFCD81528643
化学结构图
SMILES: CO[C@@H]1O[C@H](OC(C)=O)[C@@]23OCC[C@H]2[C@H](C)CC[C@H]3[C@H]1C |&1:2,4,9,13,14,18,19|
化学属性
| Mol. Weight | 298 |
|---|---|
| Mol. Formula | C16H26O5 |
别名和识别编码
| CAS Number | 181528-64-3 |
|---|---|
| Chemical Name | Artemether Tetrahydrofuran Acetate |
| Synonym | (3aS,4R,6aS,7R,8S,10R,10aR)-Octahydro-8-methoxy-4,7-dimethyl-2H,10H-furo[3,2-i][2]benzopyran-10-ol 10-Acetate, [3aS-(3a?,4?,6a?,7?,8?,10?,10aS*)]-Octahydro-8-methoxy-4,7-dimethyl-2H,10H-furo[3,2-i][ |
| Chemical Name Translation | |
| MDL Number |
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分类
- Chiral Reagents
- Heterocycles
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.
相关文献及参考
- Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998); Blum, W. et al.: J. Chrom. B Biomed. Sci. Appl., 710, 101 (1998);
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