N,N'-((Thiobis(Ethane-2,1-Diyl))Bis(1,3,4-Thiadiazole-5,2-Diyl))Bis(2-Phenylacetamide) N,N’-(硫基双(乙烷-2,1-二基))双(1,3,4-噻二唑-5,2-二基))双(2-苯基乙酰胺)

CAS 314045-39-1 MFCD14045391

化学结构图

314045-39-1
SMILES:

化学属性

Mol. FormulaC24H28N6O2S3

别名和识别编码

Chemical NameN,N'-((Thiobis(Ethane-2,1-Diyl))Bis(1,3,4-Thiadiazole-5,2-Diyl))Bis(2-Phenylacetamide)
Chemicalbook IDCB22654238
Chemical Name TranslationN,N’-(硫基双(乙烷-2,1-二基))双(1,3,4-噻二唑-5,2-二基))双(2-苯基乙酰胺)
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相关文献及参考

  • [2]. Meghan J. Seltzer, et al. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res. 2010 Nov 15; 70(22): 8981-8987.
  • [3]. Lee JS, et al. Glutaminase 1 inhibition reduces thymidine synthesis in NSCLC. Biochem Biophys Res Commun. 2016 Aug 26;477(3):374-82
  • [4]. Lee JS, et al. Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC. Cell Death Dis. 2016 Dec 8;7(12):e2511.
  • [1]. Elgogary A, et al. Combination therapy with BPTES nanoparticles and targets the metabolic heterogeneity of pancreatic cancer. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5328-36.
  • [1]. Elgogary A, et al. Combination therapy with BPTES nanoparticles and targets the metabolic heterogeneity of pancreatic cancer. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5328-36.
  • [2]. Meghan J. Seltzer, et al. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Glutaminase  (谷氨酰胺酶)

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