2?-C-?-Methyl Guanosine
CAS 374750-30-8 MFCD74750308
化学结构图
SMILES: C[C@@]1(O)[C@H](O[C@@H](CO)C1O)N1C=NC2C(=O)N=C(N)NC1=2 |&1:1,3,5|
化学属性
| Mol. Weight | 297.27 |
|---|---|
| Mol. Formula | C11H15N5O5 |
别名和识别编码
| CAS Number | 374750-30-8 |
|---|---|
| Chemical Name | 2?-C-?-Methyl Guanosine |
| Synonym | 2'-C-Methylguanosine |
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分类
- Carbohydrates & Derivatives
- Heterocycles
- Nucleotides
- Bases & Related Reagents
产品应用
- 2?-C-?-Methyl Guanosine is an anti-HCV agent. 2?-C-?-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus.
相关文献及参考
- Pudlo, J., et al.: J. Med. Chem., 33, 1984 (1990),
- Takamizawa, A., et al.: J. Virol., 65, 1105 (1991),
- Dhanak, D., et al.: J. Biol. Chem., 277, 38322 (2002),
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