KU-0058684 is a potent PARP and DNA-PK inhibitors.

CAS 623578-11-0 MFCD23578110

化学结构图

623578-11-0
SMILES: O=C1CCC(=O)N1c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

化学属性

Mol. Weight351.33
Appearance Solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical NameKU-0058684 is a potent PARP and DNA-PK inhibitors.
FormulaC19H14FN3O3
Synonym KU0058684; KU-0058684; KU 0058684; KU58684; KU 58684; KU-58684
IUPAC Name1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl)pyrrolidine-2,5-dione
InChIKeyYQSZNYLPVBOGPO-UHFFFAOYSA-N
InChIInChI=1S/C19H14FN3O3/c20-14-6-5-11(10-16(14)23-17(24)7-8-18(23)25)9-15-12-3-1-2-4-13(12)19(26)22-21-15/h1-6,10H,7-9H2,(H,22,26)
Canonical SMILESO=C(CC1)N(C2=CC(CC3=NNC(C4=C3C=CC=C4)=O)=CC=C2F)C1=O
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产品应用

  • KU-0058684 is a potent PARP and DNA-PK inhibitors.

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Medical Research Areas
  2. DNA Damage
  3. DNA-PK
  1. Medical Research Areas
  2. DNA Damage
  3. PARP
  1. Medical Research Areas
  2. PI3K/AKT/mTOR
  3. DNA-PK

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