Phenylarsine Oxide 氧化苯胂

CAS 637-03-6 MFCD00001990

化学结构图

637-03-6
SMILES: O=[As]c1ccccc1

化学属性

Mol. FormulaC6H5AsO
Mol. Weight168
Melting Point140-160°
TSCAYes
SolubilityDMSO: 50 mg/mL
Appearance powder

别名和识别编码

Chemical NamePhenylarsine Oxide
Synonym Oxophenylarsine Poly α-olefins PHENYLARSINE OXIDE(PAO) Phenyl arsine oxide oxophenyl-arsin PHENYLARSINE OXIDE, TECH. ARZENE PHENYLARSINE OXIDE SOLUTION, 0.00564 N Phenylarsine oxide solution Arzene arsenoso-benzen Arzene Oxophenylarsine PAO PHENYL ARSENE OXIDE Fenylarsinoxid 氧化苯胂 Arsenosobenzene POTASSIUM THIOCYANATE, REAGENTPLUS TM, >= 99.0% PHENYLARSINE OXIDE Polyalphaolefins Phenylarsineoxide,97% PAO 苯基氧化砷 氧化苯砷 Benzene, arsenoso- 苯砷氧 fenylarsinoxid OXOPHENYLARSINE Phenylarsenoxide 苯胂化氧 PHENYLARSINE OXIDE (ARZENE, PAO, OXOPHEN phenylarsine oxide, mixture of oligomers PHENYL ARSENOXIDE
CAS Number637-03-6
PubChem Substance ID4778
EC Number211-275-3
Beilstein Registry Number16(1)438
MDL NumberMFCD00001990
Reaxys-RN2935227
Merck Number6949
Chemical Name Translation氧化苯胂
Wiswesser Line NotationO-AS-R
LabNetwork Molecule IDLN00194431
InChIInChI=1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Embryonic Stem Cell Biology Growth Factors, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, General Stem Cell Biology, Kinase/Phosphatase Biology, Mesenchymal Stem Cell Biology, Mesenchymal Stem Cell Biology Growth Factors, P, P to Q, Phosphatase Inhibitors, Phosphorylation Analysis, Post-Translational Modification, Protein phosphatase, tyrosine, Proteomics, Stem Cell Biology, Stem Cell Reprogramming, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology,
  • {SNA} Bioactive Small Molecules,

相关文献及参考

  • Hmadcha, et al., Phenylarsine oxide increases intracellular calcium mobility and Inhibits Ca 2+ -dependent ATPase activity in thymocytes. Mol. Genet. Metab. 68 , 363-370, (1999) 摘要
  • Jenkins, et al., Modulation of tau phosphorylation within its microtubule-binding domain by cellular thiols. J. Neurochem. 73 , 1843-1850, (1999) 摘要
  • Wachtel, et al., Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J. Cell Sci. 112 , 4347-4356, (1999) 摘要
  • Christen, E.H., et al., A General Strategy For The Production Of Difficult-to-express Inducer-dependent Bacterial Repressor Proteins In Escherichia Coli. Protein Expr. Purif. 66 , 158-64, (2009) 摘要
  • Merck 14 ,6949
  • Beil. 16 ,IV,1160
  • FT-IR 1 (2), 1141:D / RegBook 1 (2), 3039:J / Structure Index 1 , 481:A:3

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T,N
Hazard statements
  • H301+H331
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H331 Toxic if inhaled 吸入中毒
  • H301 Toxic if swallowed 吞食有毒
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P308+P313
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P405 Store locked up. 上锁保管。
  • P304+P340+P311
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310+P330
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P301+P310
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
Signal word Danger {} {} {} {} {} {} {TCI}
RTECSCH8100000
UN Number UN3465 3465 UN 3465 6.1/PG 3
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S20/21 When using do not eat, drink or smoke 使用时，不得进食，饮水或吸烟；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R50/53
Packing GroupIII
Hazard Class6.1
Storage condition Poison room 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1570 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHBUA9 Pharmaceutical Bulletin.  (Tokyo, Japan)  V.1-5, 1953-57.  For
   publisher information, see CPBTAL.  Volume(issue)/page/year: 2,19,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 70,221,1940

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 790 ug/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 69,342,1940

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1930 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 74,210,1942

其他信息

  • TCI Shanghai:氧化苯砷 Phenylarsine Oxide,>;97.0%(T)(637-03-6)
  • color:white to yellow
  • Sigma Aldrich:637-03-6(sigmaaldrich)
  • Acros Organics:氧化苯胂 Phenylarsine oxide, 97%(637-03-6)
  • 用途一:用于有机合成。该品剧毒，用作杀虫剂。
  • 上游原料:碘化钾 --> 二氧化硫 --> 苯胂酸
  • MOL 文件:637-03-6.mol
  • 方法一:将苯砷酸、甲醇、浓盐酸按重量比1：5：2混合，加入少许碘化钾，然后通入二氧化硫至饱和。将反应生成的油状苯二氯砷用氢氧化钠溶液溶解，再用盐酸中和，使苯砷氧沉淀出来。
  • 外观性质:白色结晶粉末。
  • MSDS 信息:苯胂化氧(637-03-6).msds
  • 图谱信息:氧化苯胂(637-03-6)质谱(MS) 氧化苯胂(637-03-6)红外图谱(IR1) 氧化苯胂(637-03-6)红外图谱(IR2) 氧化苯胂(637-03-6)红外图谱(IR3)
  • 氧化苯胂价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0140 氧化苯砷 Phenylarsine Oxide 5G 774元 2010/06/21 180350010 氧化苯胂 Phenylarsine oxide 97% 1 GR 505元 2010/06/21 180350050 氧化苯胂 Phenylarsine oxide 97% 5 GR 1069元
  • Alfa Aesar:氧化苯砷,97% Phenylarsine oxide, 97%(637-03-6)

系列性分类

  1. Chemical Synthesis 化学合成
  2. Catalysis and Inorganic Chemistry 催化剂和无机化学
  3. Arsenic - Catalysis and Inorganic Chemistry
  1. Chemical Synthesis 化学合成
  2. Catalysis and Inorganic Chemistry 催化剂和无机化学
  3. Sodium - Catalysis and Inorganic Chemistry
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Inorganic Acids - Synthetic Reagents
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Inorganic Bases - Synthetic Reagents
  1. Labware 实验室仪器设备与耗材
  2. Manufacturer Browser - Labware
  3. Labconco - Manufacturer Browser
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. DNA & RNA Purification - Molecular Biology
  4. Reagents - DNA & RNA Purification
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. ACS - Analytical Reagents for General Use
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. - Analytical Reagents for General Use
  1. Research Essentials 基础科研
  2. Essential Chemicals - Research Essentials
  3. Inorganic Salts, Solutions and Reagents - Essential Chemicals
  4. Sodium Hydroxide (NaOH) and Sodium Hydroxide Solutions - Inorganic Salts, Solutions and Reagents
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Titration - Analytical Reagents
  4. Volumetric Solutions - Titration
  5. Salt Solutions - Volumetric Solutions
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Arsenic Compounds 砷化合物
  1. Analytical & Chromatography 分析化学与色谱
  2. HPLC
  3. Buffers & Reagents - HPLC
  4. HPLC Buffers - Buffers & Reagents
  5. HPLC Buffers - Solution - HPLC Buffers
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. P to Q - Enzyme Inhibitors by Enzyme
  7. Protein phosphatase, tyrosine - P to Q
  1. Life Science 生命科学
  2. Plant Biotechnology 植物生物技术
  3. Plant Molecular Biology - Plant Biotechnology
  4. Plant Nucleic Acid Purification - Plant Molecular Biology
  5. Reagents - Plant Nucleic Acid Purification
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Electrophoresis - Proteomics
  4. Isoelectric Focusing and Two Dimensional Electrophoresis - Protein Electrophoresis
  5. Electrode Buffers - Isoelectric Focusing and Two Dimensional Electrophoresis
  1. Analytical & Chromatography 分析化学与色谱
  2. Gas Chromatography (GC) 气相色谱
  3. Gas Purification/Management - Gas Chromatography (GC)
  4. Purifiers - Gas Purification/Management
  5. In-Line Purifiers (Remove a Single Contaminant) - Purifiers
  6. Carbon Dioxide Trap - In-Line Purifiers (Remove a Single Contaminant)
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Tyrosine Phosphatase Biology - Kinase/Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors - Tyrosine Phosphatase Biology
  7. Tyrosine Phosphatase (TP) - Tyrosine Phosphatase Inhibitors
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Tyrosine Phosphatase Biology - Kinase/Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors - Tyrosine Phosphatase Biology
  7. Tyrosine Phosphatase (TP) - Tyrosine Phosphatase Inhibitors
  1. Analytical & Chromatography 分析化学与色谱
  2. Acids & Bases
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. BioChemika Ultra
  4. Luminescence Spectroscopy Reagents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Metal Compounds 金属化合物
  1. Analytical & Chromatography 分析化学与色谱
  2. Adsorbents, Filter Aids and Drying Agents
  3. Molecular Sieves
  1. Analytical & Chromatography 分析化学与色谱
  2. Adsorbents, Filter Aids and Drying Agents
  3. Other Drying Agents
  1. Analytical & Chromatography 分析化学与色谱
  2. Titration
  3. Volumetric Solutions
  4. Acid Solutions
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Acids & Bases
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Molecular Biology
  4. Protein Electrophoresis
  5. Capillary Electrophoresis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Plant Biotechnology
  4. Plant Proteomics
  5. Protein Electrophoresis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Proteomics
  4. Post-Translational Modification
  5. Phosphorylation Analysis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Proteomics
  4. Protein Electrophoresis
  5. Capillary Electrophoresis
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Kinase/Phosphatase Biology
  5. Tyrosine Phosphatase Biology
  6. Tyrosine Phosphatase Inhibitors
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Kinase/Phosphatase Biology
  5. Non-Receptor Tyrosine Kinase Biology
  6. Non-Receptor Tyrosine Kinase Inhibitors
  7. Lymphocyte Specific Kinase and Spleen Tyrosine Kinase (Lck, Syk)
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Inhibitors
  5. Enzyme Inhibitors by Enzyme
  6. Protein kinase, tyrosine
  7. competitive inhibitor of ATP

相关产品推荐

98-05-5
122-39-4
24677-78-9
143-74-8
2402-78-0
619-23-8
329-98-6
610-94-6
59-23-4
34487-61-1
59-23-4