2,4,6-Trichlorophenol 2,4,6-三氯酚

CAS 88-06-2 MFCD00002172

化学结构图

88-06-2
SMILES: Oc1c(Cl)cc(Cl)cc1Cl

化学属性

Mol. FormulaC6H3Cl3O
Mol. Weight197.44
Boiling Point120°C/39mmHg(lit.)
Melting Point65.0 to 69.0 deg-C
Density1.0
Flash Point99°(210°F)
TSCAYes
Vapor Pressure1 mmHg ( 76.5 °C)
Solubility0.8 g/L

别名和识别编码

Chemical Name2,4,6-Trichlorophenol
CAS Number88-06-2
PubChem Substance ID6914
EC Number201-795-9
Beilstein Registry Number6,190
MDL NumberMFCD00002172
Synonym 2,4,6-三氯苯酚;2,4,6-三氯酚 caswellno.880c 2,4,6 T 6-三氯苯酚 Dowcide 2S RCRA waste number U231 1,3,5-Trichloro-2-hydroxybenzene 2,4,6-三氯苯酚 2,4,6-三氯苯酚, 98% NCI-C02904 2,4,6-Trichlorfenol dowcide2s 2,4,6-三氯酚 DOWICIDE 2S ai3-00142 PHENACHLOR Dowicide 2S 2 2,4,6-trichloro-pheno 2,4,6-trichloro-2-hydroxybenzene epapesticidechemicalcode064212 2,4,6-三氯苯酚 DOWICIDE 2S(R) 2,4,6-三氯酚 056-01 [6] 2,4,6-trichlorfenol(czech) 1,3,5-Trichlorophenol 2,4,6-Trichlorophenol TRICHLOROPHENOL(2,4,6-) 2,4,6-TCP 2,4,6-三氯酚 4 OMAL 6-三氯酚 Phenachlor 2,4,6-TRICHLOROPHENOL
Reaxys-RN776729
Merck Number9644
Chemical Name Translation2,4,6-三氯酚
Wiswesser Line NotationQR BG DG FG
LabNetwork Molecule IDLN00193604
InChIInChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
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分类

  • {SNA} Analytical Standards, Chromatography, Environmental Standards, Q-Z, Standards for Personal Care and Cosmetic Products, neats, prohibited substances (EU-REGULATION No 1223/2009), 农残和代谢标准品, 分析/色谱, 按照字母排序
  • {SNA} Analytical Standards,
  • {
  • {SNA} Building Blocks
  • {SNA} Alphabetical Index of Analytical Standards, All alphabetically sorted, Analytical Standards, Analytical/Chromatography, Chromatography,
  • {Chemicalbook} 农药中间体: 杀菌剂中间体: 三唑类杀菌剂
  • {SNA} Additional Standards,
  • {SNA} Analytical Standards, Certified Reference Materials (CRMs), Chromatography, Fluka CRMs for Chromatography (neats), Organic CRMs TraceCERT, Standards for Personal Care and Cosmetic Products, neats,

产品应用

  • 农药、医药中间体

相关文献及参考

  • Merck: 14,9644 Beilstein:6,190
  • Merck: 14,9644

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H315 Causes skin irritation 会刺激皮肤
  • H351 Suspected of causing cancer 怀疑致癌
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Hazard Codes Xn,N,T,F
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P308+P313
  • P332+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P312+P330
  • P337+P313
  • P305+P351+P338
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P305+P351+P338+P337+P313
  • P302+P352+P312+P361+P364
  • P405 Store locked up. 上锁保管。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
Signal word
RTECSSN1575000
UN Number UN 3077 9/PG 3 2020
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R22 Harmful if swallowed 吞咽有害
  • R50/53
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R11 Highly flammable 非常易燃
  • R52/53
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Packing GroupIII
Storage condition 储存温度2-8℃ 0-6°C
Hazard Class6.1
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 185 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 882 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 441 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-155,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 374 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/y

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C310,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 454 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),16,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,1176,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 276 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 13,20,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kil

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 30 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,175,1992

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   69,333,1989

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 303,101,1993

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 400 mg/L
REFERENCE :
   EVSRBT Environmental Science Research.  (Plenum Pub. Corp., 233 Spring St.,
   New York, NY 10013) V.1-    1972-  Volume(issue)/page/year: 12,325,1978

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 80 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,85,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 400 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 303,101,1993

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 12500 mg/kg
SEX/DURATION            : female 2 week(s) pre-mating
                          female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   6,233,1986

Warnings 危险化学品

其他信息

  • MSDS 信息:2,4,6-三氯苯酚(88-06-2).msds
  • 外观性质:无色针状结晶或黄色固体,有强烈的苯酚气味。
  • 毒性分级:中毒
  • 急性毒性:口服-大鼠 LD50: 820 毫克/公斤; 腹腔-大鼠 LD50: 276 毫克/公斤
  • 用途二:2,4,6-三氯苯酚是杀菌剂咪鲜胺和除草剂草枯醚的中间体。
  • 用途一:主要用于杀菌剂、保鲜剂咪鲜胺的主要原料
  • TCI Shanghai:2,4,6-三氯苯酚 2,4,6-Trichlorophenol,>;96.0%(GC)(88-06-2)
  • 类别:有毒物品
  • 用途三:医药中间体。
  • 方法一:其制备方法是将苯酚放入反应器中,通入氯气,通氯气时间约12h,前期反应温度60~65℃,后期2~3h为70~75℃,通氯气结束后保温1h,通入氯气的量为苯酚物质的量的3倍,中途严格跟踪分析,防止氯气过量,然后通入氮气赶除多余的氯气和氯化氢,反应后的粗品经亚硫酸钠处理,然后蒸馏得产品。
  • 溶解度:800 mg/l 水;525 g/100g丙酮; 113g/100g苯;37g/100gCCl4; 335g/100g二丙酮醇; 354g/100g醚;525g/100g甲醇; 163g/100g松油; 100g/100g甲苯;37g/100g松节油,溶于芳香族溶剂和腐蚀性的苏达溶液。
  • MOL 文件:88-06-2.mol
  • 刺激数据:皮肤-兔子 20 毫克/24小时 中度; 眼睛-兔子 0.25 毫克/24小时 重度
  • 可燃性危险特性:明火可燃; 受热放出有毒氯化物气体
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • Acros Organics:2,4,6-三氯苯酚 2,4,6-Trichlorophenol, 98%(88-06-2)
  • 蒸气压:1 mm Hg ( 76.5 °C)
  • 用途四:农药、医药中间体
  • Sigma Aldrich:88-06-2(sigmaaldrich)
  • 酚类单一化合物标准液
  • 灭火剂:二氧化碳、砂土、泡沫、干粉
  • Alfa Aesar:2,4,6-三氯苯酚,98% 2,4,6-Trichlorophenol, 98%(88-06-2)
  • 上游原料:盐酸 --> 苯酚 --> 磺酸
  • 用途五:用作染料中间体、杀菌剂、防腐剂,也用作聚酯纤维的溶剂。校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。
  • 图谱信息:2,4,6-三氯酚(88-06-2)红外图谱(IR1) 2,4,6-三氯酚(88-06-2)红外图谱(IR2) 2,4,6-三氯酚(88-06-2)红外图谱(IR3) 2,4,6-三氯酚(88-06-2)核磁图( 13 CNMR) 2,4,6-三氯酚(88-06-2)Raman光谱 2,4,6-三氯酚(88-06-2)质谱(MS) 2,4,6-三氯酚(88-06-2)核磁图( 1 HNMR)
  • color:white to slightly brown
  • 2,4,6-三氯酚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 C139481000 2,4,6-三氯苯酚 100g 551元 2011/08/23 AT5530101 2,4,6-三氯苯酚 98% 50g 342元 2011/08/23 K9134001 2,4,6-三氯苯酚 50g 350元
  • 海关编码:29081000
  • 下游产品:2,4-二氯酚 --> 2-(2,4,6-三氯苯氧基)乙基氯 --> 2-(2,4,6-三氯苯氧基)乙基溴 --> 咪酰胺 --> 4-氰基四氢吡喃

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