2-(5-Methoxy-1H-indol-3-yl)ethanamine 5-甲氧基色胺

CAS 608-07-1 MFCD00005662

化学结构图

608-07-1
SMILES: COc1ccc2[nH]cc(CCN)c2c1

化学属性

Mol. FormulaC11H14N2O
Mol. Weight190
Melting Point121
Density1.422
Appearance crystalline
Stability对热敏感

别名和识别编码

Chemical Name2-(5-Methoxy-1H-indol-3-yl)ethanamine
CAS Number608-07-1
Alfabeta NameMETHOXYINDOLYLETHANAMINE H2513()------
MDL NumberMFCD00005662
Synonym 2-(5-Methoxyindol-3-yl)ethylamine 3-(2-Aminoethyl)-5-methoxyindole METHOXYTRYPTAMINE, 5- MEXAMINE HYDROCHLORIDE Methoxytryptamine
EC Number210-153-7
Beilstein Registry Number145587
PubChem Substance ID87572235
Reaxys-RN145587
Chemical Name Translation5-甲氧基色胺
Merck Number13,6032
InChIKeyJTEJPPKMYBDEMY-UHFFFAOYSA-N
LabNetwork Molecule IDLN00001024
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分类

  • {SNA} Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Indoles
  • {SNA} Bioactive Small Molecules, Building Blocks, C11, Cell Biology, Chemical Synthesis, Heterocyclic Building Blocks, Indoles, M
  • {SNA} Bioactive Small Molecules, Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Indoles, M, 细胞生物学

产品应用

  • 5-Methoxytryptamine was used as an agonist in the study of pharmacological profile of the 5-hydroxytryptamine 1 receptor

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSNL4059000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Storage condition 0-10 0-10°C 2-8°C 储存温度2-8℃
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 176 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 1,515,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 106 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 27,681,1964

TYPE OF TEST            : Morphological transformation
ROUTE OF EXPOSURE       : Subcutaneous
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
REFERENCE :
   EKSODD Eksperimental'naya Onkologiya.  Experimental Oncology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Mosow, USSR)  V.1-    1979-
   Volume(issue)/page/year: 7(4),26,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 240 mg/kg
SEX/DURATION            : female 1-2 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JNTMAH Journal of Neural Transmission.  (Springer-Verlag, Postfach 367,
   A-1011 Vienna, Austria) V.33-77, 1972-89.  Volume(issue)/page/year:
   96,19,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8 mg/kg
SEX/DURATION            : male 20 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   BIREBV Biology of Reproduction.  (Soc. for the Study of Reproduction, 309 W.
   Clark St., Champaign, IL 61820)  V.1-    1969-  Volume(issue)/page/year:
   33,618,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 11 mg/kg
SEX/DURATION            : female 12-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   DBRRDB Developmental Brain Research.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1981-  Volume(issue)/page/year:
   59,59,1991

其他信息

  • 图谱信息:5-甲氧基色胺(608-07-1)红外图谱(IR1) 5-甲氧基色胺(608-07-1)红外图谱(IR2) 5-甲氧基色胺(608-07-1)质谱(MS)
  • 5-Methoxytryptamine, nonselective serotonin receptor agonist that lacks affinity for the 5-HT3 receptor
  • F:8
  • MOL 文件:608-07-1.mol
  • color:white
  • 5-甲氧基色胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0131 5-甲氧基色胺 5-Methoxytryptamine 5G 3330元 2014/06/02 M0131 5-甲氧基色胺 5-Methoxytryptamine 1G 1180元 2014/06/02 M0131 5-甲氧基色胺 5-Methoxytryptamine 100MG 403元
  • MSDS 信息:5-Methoxytryptamine (608-07-1).msds
  • 用途一:用作有机合成中间体
  • TCI Shanghai:5-甲氧基色胺 5-Methoxytryptamine,>;98.0%(T)(608-07-1)
  • 检测方法:HPLC,NMR
  • Sigma Aldrich:608-07-1(sigmaaldrich)
  • 5-甲氧基色胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 M0131 5-甲氧基色胺 5-Methoxytryptamine 5G 2740元 2011/04/16 M0131 5-甲氧基色胺 5-Methoxytryptamine 1G 971元 2011/04/16 M0131 5-甲氧基色胺 5-Methoxytryptamine 100MG 332元

系列性分类


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