• 原料直供
• 试剂商城
• 直接询价

分类

• Alkaloid, Alkaloids, Alphabetic, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Botanicals, Cell Biology, Chemical Structure, Chromatography, Drugs & Metabolites,
• {uni_hamburg} no charge; nitrogen heterocycle; aromatic; alicycle; 5ring; 6ring; chiral; 1fragment
• {SA} Alkaloid, Asymmetric Synthesi
• {SNA} Agonists, Alkaloid, Bioactive Small Molecule Alphabetical Index, Cholinergics, N, Neuroscience, Neurotransmission, Neurotransmitters, Phytochemicals by Chemical Classification, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 营养研究

产品应用

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相关文献及参考

• Geffken, D., et al.: Am. J. Epidemiol., 153, 242
• Sihver, W., et al., Autoradiographic comparison of [ 3 H](-)nicotine, [ 3 H]cytisine and [ 3 H]epibatidine binding in relation to vesicular acetylcholine transport sites in the temporal cortex in Alzheimer's disease. Neuroscience 94 , 685-696, (1999)
• Girod, R., et al., Heteromeric complexes of α5 and/or α7 subunits. Effects of calcium and potential role in nicotine-induced presynaptic facilitation. Ann. N.Y. Acad. Sci. 868 , 578-590, (1999) 摘要
• Brioni, J.D., et al., The pharmacology of (−)-nicotine and novel cholinergic channel modulators. Adv. Pharmacol. 37 , 153-214, (1997) 摘要
• Lena, C., and Changeux, J.P., Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders. Curr. Opin. Neurobiol. 7 , 674-682, (1997) 摘要
• Haass, M., and Kubler, W., Nicotine and sympathetic neurotransmission. Cardiovasc. Drugs Ther. 10 , 657-665, (1997) 摘要
• Merck 14 ,6524
• Short: III/38A Title: Refractive Indices of Inorganic, Organometallic, and Organononmetallic Liquids and Binary Liquid Mixtures Author: Wohlfarth, Ch.; Wohlfarth, B. Editor: Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/38A Year: 1996 Keyword: organicmetallic compounds; inorganic compounds; refractive index; liquids; mixtures ISBN: 3-540-60539-8 ISBN: 978-3-540-60539-3 Internet Resource: DOI:10.1007/b55612 RefComment: VII, 400 pages, Hardcover Abstract: Volume III/38 Optical Constants provides critically evaluated data on refractive indices of inorganic and organic liquids and their wavelength dependence (dispension). Part A contains the inorganic, organometallic, and organononmetallic liquids, and the binary liquid mixtures (about 900 pure substances and their mixtures). Part B contains data of more than 7600 organic liquids.

安全信息

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Rectal
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1430 ug/kg
TOXIC EFFECTS :
   Behavioral - hallucinations, distorted perceptions
   Gastrointestinal - nausea or vomiting
REFERENCE :
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 10,391,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14560 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 124,350,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C219,1991

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 882 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
   Springfield, IL, C.C. Thomas, 1970  Volume(issue)/page/year: 2,73,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATIO

其他信息

• 下游产品:烟酸
• MOL 文件:54-11-5.mol
• 图谱信息:烟碱(54-11-5)核磁图( 1 HNMR) 烟碱(54-11-5)核磁图( 13 CNMR) 烟碱(54-11-5)红外图谱(IR1) 烟碱(54-11-5)质谱(MS)
• 方法一:烟碱在烟草中含量平均达4%，在植物中以柠檬酸盐或苹果酸盐形式存在。工业上可利用制废料，用简单的水蒸气蒸馏提取。
• 上游原料:烟草 --> 柠檬酸盐
• 爆炸物危险特性:与空气混合可爆
• MSDS 信息:尼古丁(54-11-5).msds
• 毒性分级:剧毒
• Acros Organics:剧毒品不能订 L-Nicotine,99+%(54-11-5)
• 可燃性危险特性:明火可燃; 与氧化剂反应; 高热分解放出有毒氮氧化物气体
• 烟碱价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 181420050 烟碱 L-Nicotine 99+% 5 GR 823元 2010/06/21 181420250 烟碱 L-Nicotine 99+% 25 GR 1653元 2010/06/21 181421000 烟碱 L-Nicotine 99+% 100 GR 2824元
• 急性毒性:口服- 大鼠 LD50: 50 毫克/ 公斤; 口服- 小鼠 LD50:3.34 毫克/ 公斤
• 比旋光度:-166 ° (c=neat)
• 储运特性:库房通风低温干燥; 与氧化剂、酸类、食品添加剂分开存放
• 类别:农药
• color:yellow
• 敏感性:Air Sensitive & Hygroscopic
• 职业标准:TLV-TWA 0.5 毫克/ 立方米; STEL 1.5 毫克/ 立方米
• 用途一:烟碱是一种吡啶型生物碱，曾用作园艺上的杀虫剂。烟碱经氧化可制得烟酸，用作医药、食品和饲料添加剂。
• 灭火剂:干粉、泡沫、二氧化碳、砂土、抗溶性泡沫。
• 外观性质:纯品为无色油状液体，有焦灼味，工业品为棕色。
• Sigma Aldrich:54-11-5(sigmaaldrich)
• Alfa Aesar:(S)-(-)-烟碱/尼古丁,99% (S)-(-)-Nicotine, 99%(54-11-5)