N-Succinimidyl 4-(N-Maleimidomethyl)Cyclohexane-1-Carboxylate 4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯

CAS 64987-85-5 MFCD00009634

化学结构图

64987-85-5
SMILES: O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1

化学属性

Mol. FormulaC16H18N2O6
Mol. Weight334
Melting Point176-180
TSCANo
Density1.422

别名和识别编码

Chemical NameN-Succinimidyl 4-(N-Maleimidomethyl)Cyclohexane-1-Carboxylate
CAS Number64987-85-5
Synonym 4-(N-Maleimidomethyl)-cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid N-Hydroxysuccinimide Ester 4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯 N-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯 SMCC SMCC
PubChem Substance ID135727275
Beilstein Registry Number1555271
MDL NumberMFCD00009634
Reaxys-RN1555271
EC Number250-023-7
Chemical Name Translation4-(N-马来酰亚胺基甲基)环己烷-1-羧酸琥珀酰亚胺酯
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分类

  • {SNA} Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Crosslinking Reagents, Heterobifunctional Cross-Linking Reagents, Heterobifunctional Crosslinking Reagents, Linkers and Crosslinkers, Molecular Biology, Protein Interaction, Protein Modification, Protein Structural Analysis,

产品应用

  • A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab?)2 fragments to ?-galactosidase. Conjugates hIgG to alkaline phosphatase.

相关文献及参考

  • ########
  • Yoshitake, S., et al., Mild and efficient conjugation of rabbit Fab' and horseradish peroxidase using a maleimide compound and its use for enzyme immunoassay. J. Biochem. 92 , 1413-1424, (1982) 摘要
  • Corp MSDS 1 (2), 2186:A / RegBook 1 (1), 929:C / Sigma FT-IR 1 (2), 692:A / Structure Index 1 , 144:A:6

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P405 Store locked up. 上锁保管。
  • P501a
Signal word Warning
Storage condition <;0 Moisture & Light Sensitive <0°C
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Interaction - Proteomics
  4. Crosslinking Reagents - Protein Interaction
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Crosslinking - Protein Modification
  6. Heterobifunctional Cross-Linking Reagents - Crosslinking

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