4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠 4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠

CAS 207233-90-7 MFCD00009638

化学结构图

207233-90-7
SMILES: [Na+].[Na+].[O-]S(=O)(=O)C1=CC(=CC=C1/C=C/C1=CC=C(C=C1S([O-])(=O)=O)N=C=S)N=C=S

化学属性

Mol. FormulaC16H8N2Na2O6S4·xH2O
Mol. Weight498.48 (anhydrous basis)

别名和识别编码

Chemical Name4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate
Synonym 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate DIDS Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate DIDS Disodium 4,4'-diisothiocyanatostilbene-2,2'-disulfonate DIDS, Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate
CAS Number207233-90-7
PubChem Substance ID24893761
Beilstein Registry Number8179433
MDL NumberMFCD00009638
Chemical Name Translation4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠
Reaxys-RN8179433
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分类

  • {SA} Biochemicals and Reagents, Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Homobifunctional Cross-Linking Reagents, Linkers and Crosslinkers, Other Fluorescent Labels,
  • {SNA} Amine to Amine, Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking, Fluorescent Labels, Homobifunctional Cross-Linking Reagents, Linkers and Crosslinkers, Other Fluorescent Labels, Protein Modification, 分子生物学, 生化试剂, 荧光探针，标记，粒子和染色剂, 蛋白质组学, 蛋白质结构分析
  • {SNA} Biochemica

相关文献及参考

  • Okada, Y., et al., Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. J. Membr. Biol. 209 , 21-29, (2006) 摘要
  • Pusch, M., et al., Channel or transporter? The CLC saga continues. Exp. Physiol. 91 , 149-152, (2006) 摘要
  • Alper, S.L., Molecular physiology of SLC4 anion exchangers. Exp. Physiol. 91 , 153-161, (2006) 摘要
  • Hua, S., and Inesi, G., Lys515-Lys492 cross-linking by DIDS interferes with substrate utilization by the sarcoplasmic reticulum ATPase. Biophys. J. 73 , 2149-2155, (1997) 摘要
  • Kavanaugh, M.P., et al., Affinity labeling of hemoglobin with 4,4'-diisothiocyanostilbene-2,2'-disulfonate: covalent cross-linking in the 2,3-diphosphoglycerate binding site. Biochemistry 27 , 1804-1808, (1988)

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P342+P311
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Signal word Danger
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
Storage condition 0-10°C

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Fluorescent Labels - Fluorescent Probes, Labels, Particles and Stains
  5. Other Fluorescent Labels - Fluorescent Labels
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. Protein Modification - Protein Structural Analysis
  5. Crosslinking - Protein Modification
  6. Homobifunctional Cross-Linking Reagents - Crosslinking
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Stilbenes
  1. Functional Group 官能团索引
  2. isothiocyanate
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Fluorescent Labels
  5. Fluorescein and Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Functional Group Reactive Labels
  5. Functional Group Reactive Labels for Microscopy
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Fluorescent Indicators and Probes
  5. Lipophilic and Membrane Probes
  6. Environmental Sensitive Membrane Probes
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Fluorescent Stains
  5. Protein Stains
  6. Protein Stains for Microscopy
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Indicators and Probes
  6. Chelators and Ion Probes
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Labels
  6. Fluorescein and Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Functional Group Reactive Labels
  6. Functional Group Reactive Labels for Microscopy
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Stains
  6. Protein Stains
  7. Protein Stains for Microscopy

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