Sulfisomidin 磺胺索嘧啶
CAS 515-64-0 MFCD00010567
化学结构图
SMILES: CC1=CC(NS(=O)(=O)C2C=CC(N)=CC=2)=NC(C)=N1
化学属性
| Mol. Formula | C12H14N4O2S |
|---|---|
| Mol. Weight | 278.33 |
| Melting Point | 242-243 °C(lit.) |
别名和识别编码
| Chemical Name | Sulfisomidin |
|---|---|
| MDL Number | MFCD00010567 |
| CAS Number | 515-64-0 |
| Synonym | (p-Aminobenzolsulfonyl)-4-amino-2,6-dimethylpyrimidin Sulfaisodimerazine 6-Sulfanilamido-2,4-dimethylpyrimidine 磺胺索嘧啶 Aristogyn Sulfasomidine Domian Aristamid Elkosine 6-(4-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine 2,4-Dimethyl-6-sulfanilamidopyrimidine Sulfisomidin 6-(p-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine Sulfamethin Benzenesulfonamide, 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)- Erycon 4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide Mefenal Sulfaisodimidine N(sup 1)-(2,6-Dimethyl-4-pyrimidinyl)sulfanilamide 4-Sulfa-2,6-dimethylpyrimidine Sulphasomidine Sulfisomidine 2,6-Dimethyl-4-sulfanilamidopyrimidine 4-氨基-N-(2,6-二甲基-4-嘧啶基)苯磺酰胺 N1-(2,6-二甲基嘧啶-4-基)磺胺 6-(p-Aminobenzenesulfonyl)amino-2,4-dimethylpyrimidine Sulfadimetine |
| PubChem Substance ID | 87575874 |
| Beilstein Registry Number | 25(3/4)2197 |
| EC Number | 208-204-3 |
| Reaxys-RN | 261305 |
| Merck Number | 8951 |
| Chemical Name Translation | 磺胺索嘧啶 |
| Wiswesser Line Notation | T6N CNJ B1 D1 FMSWR DZ |
| LabNetwork Molecule ID | LN01252642 |
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分类
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibiotics, Bacteriostatic, Chemical Structure, Chromatography, Clinical Standards, Principle, S, SN - SZ, Sulfonamides
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Antibiotics, Bacteriostatic, Chemical Structure, Chromatography, Clinical Standards, Principle, S, SN - SZ, Sulfonamides, 分析/色谱
- {SNA} Additional Standards, Analytical Standards, Antibiotics Stan
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE : 2500 mg/kg SEX/DURATION : female 8-12 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 43(12),10,1967
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 6 gm/kg SEX/DURATION : female 9-14 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973
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