Phenanthridinium, 3,​8-​diamino-​5-​[3-​(diethylmethylammoni​o)​propyl]​-​6-​phenyl-​, iodide (1:2) 3,8-二氨基-5-(二乙基甲基氨基丙基)-6-苯基菲啶二碘化物

CAS 25535-16-4 MFCD00011921

化学结构图

25535-16-4
SMILES: CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[I-].[I-]

化学属性

Mol. FormulaC27
Mol. Weight668
Melting Point220-225

别名和识别编码

Chemical NamePhenanthridinium, 3,​8-​diamino-​5-​[3-​(diethylmethylammoni​o)​propyl]​-​6-​phenyl-​, iodide (1:2)
CAS Number25535-16-4
Synonym 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide Propidium iodide
EC Number247-081-0
Beilstein Registry Number3843838
MDL NumberMFCD00011921
PubChem Substance ID57654524
Chemical Name Translation3,8-二氨基-5-(二乙基甲基氨基丙基)-6-苯基菲啶二碘化物
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分类

  • {SA} Alphabetical, Apoptosis Detection, Apoptosis and Cell Cycle, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Culture Supplies, Cell Signaling and Neuroscience, Cell Staining for Scale-Up Cell Culture, Fluorescent Probes, Labels, Particles and Stains, Fluorescent Stains, Hematology and Histology, Labware, Nucleic Acid Stains, P, Reagents, Scale-Up Cell Culture using Corning Roller Bottles, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} Alphabetical, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Detection, Fluorescent Enzyme Substrates,
  • {SNA} Alphabetical,

产品应用

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相关文献及参考

  • Karlsson, R., et al.: Anal. Biochem., 278, 1 (2000),
  • Lundqvist, T., et al.: Curr. Opin Drug Discov. Dev., 8, 513 (2005),
  • Elinder, M., et al.: J. Biomol. Screen, 14, 395 (2009),

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves Eyeshields, Gloves
RTECSSF7949600
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P305+P351+P338
  • P308+P313
  • P337+P313
Signal word Warning
Hazard Codes Xn Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 11,334,1956

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 200 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 127,31,1984

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 50 umol/L/3D (Continuous)
REFERENCE :
   BBRCA9 Biochemical and Biophysical Research Communications.  (Academic
   Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1959-
   Volume(issue)/page/year: 84,501,1978

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 25 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 82,87,1981

系列性分类

  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Stains and Dyes - Core Bioreagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. P - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Stains and Dyes - Hematology and Histology
  4. Stains & Dyes, A to Z - Stains and Dyes
  5. P - Stains & Dyes, A to Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Fluorescent Stains - Fluorescent Probes, Labels, Particles and Stains
  5. Nucleic Acid Stains - Fluorescent Stains
  6. Alphabetical - Nucleic Acid Stains
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Apoptosis Detection - Apoptosis and Cell Cycle
  6. Reagents - Apoptosis Detection
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Other Apoptosis Related Reagents - Apoptosis and Cell Cycle
  6. Stains - Other Apoptosis Related Reagents
  1. Functional Group 官能团索引
  2. quaternary ammonium salt

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