o-Dianisidine dihydrochloride 邻联茴香胺二盐酸盐

CAS 20325-40-0 MFCD00012488

化学结构图

20325-40-0
SMILES: Cl.Cl.COC1=CC(=CC=C1N)C1C=C(OC)C(N)=CC=1

化学属性

Mol. FormulaC14H16N2O2.2HCl
Mol. Weight317
Melting Point268
TSCAYes
Solubility溶于水、乙醇,微溶于乙醚。
Density1.178

别名和识别编码

Chemical Nameo-Dianisidine dihydrochloride
Synonym 3,3'-二甲氧基联苯胺 二盐酸盐 3,3'-二甲氧基联苯胺 二盐酸盐 固蓝 B 3,3'-Dimethoxy-(1,1-biphenyl)-4,4'-diamine dihydrochloride 3,3'-Dimethoxy-4,4'-diaminobiphenyl dihydrochloride 3,3'-Dimethoxybenzidine dihydrochloride 3,3'-二甲氧基联苯胺 二盐酸盐 3,3’-二甲氧基联苯胺盐酸盐,快蓝B 3,3′-二甲氧基联苯胺 二盐酸盐 4,4'-Diamino-3,3'-dimethoxybiphenyl Dihydrochloride, o-Dianisidine Dihydrochloride 4,4'-Diamino-3,3'-dimethoxybiphenyl dihydrochloride C.I. Disperse Black 6 dihydrochloride o-Dianisidine dihydrochloride o-Dianisidine dihydrochloride; 3,3'-Dimethoxy-[1,1'-biphenyl]-4,4'-diamine dihydrochloride 固蓝 B 联大茴香胺盐酸盐 邻联茴香胺 二盐酸盐
MDL NumberMFCD00012488
PubChem Substance ID87568134
Beilstein Registry Number3917996
EC Number243-737-5
CAS Number20325-40-0
Chemical Name Translation邻联茴香胺二盐酸盐
Reaxys-RN3917996
Wiswesser Line Notation1OR BZ ER DZ CO1 &GH 2
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} D, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学, 血液学和组织学
  • {SNA} Alphabetical Listing, Colorimetric, D, Detection, Detection Substrates, ELISA Substrates, Enzyme Substrates, Peroxidase, Powders, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞生物学, 血液学和组织学, 酶、抑制剂和底物
  • {SNA} Alphabetical Listing, Colorimetric, Detection, Detection Substrates, ELISA Substrates, Enzyme Substrates, Peroxidase,

产品应用

  • 用来鉴定金、铜、钴和钒等元素。过氧化物酶的底物

相关文献及参考

  • Beilstein: 13,IV,2834

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312+P330
  • P308+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H350 May cause cancer 可能致癌
  • H302 Harmful if swallowed 吞食有害
RTECSDD1050000
Signal word Danger
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R45 May cause cancer 可能致癌
Hazard Codes T
Storage condition 储存温度 2-8°C
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1040 mg/kg/1Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Ear) - effect, not otherwise specified
   Reproductive - Tumorigenic effects - testicular tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   41,985,1968

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11 gm/kg/51W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Ear) - effect, not otherwise specified
   Skin and Appendages - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   41,985,1968

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6497 mg/kg/91W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal -

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1152 mg/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   VOONAW Voprosy Onkologii.  Problems of Oncology.  For English translation,
   see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-10,
   1928-37; V.1-    1955-  Volume(issue)/page/year: 25(7),43,1979

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 33 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12(Suppl 13),37,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 500 ug/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-372,1990

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 nmol/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(i

{h

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-372,

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 136,33,1984

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-372,1990

TYPE OF TEST

其他信息

  • 联大茴香胺o-Dianisidine (3,3'-dimethoxybenzidine) 在ELISA酶免中是过氧化物酶的底物。 该底物产生桔黄色的可溶性的末端产物,能在405 nm处被分光光度计读取,该反应可用5 M HCl终止

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