2'-(4-Ethoxyphenyl)-5-(4-Methylpiperazin-1-Yl)-1H,1'H-2,5'-Bibenzo[D]Imidazole 2’-(4-乙氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1’H-2,5’-联苯并[d]咪唑

CAS 23491-52-3 MFCD00012678

化学结构图

23491-52-3
SMILES: Cl.Cl.Cl.CN1CCN(CC1)C1=CC2N=C(NC=2C=C1)C1=CC2N=C(NC=2C=C1)C1C=CC(=CC=1)OCC

化学属性

Mol. FormulaC27H28N6O · 3HCl · xH2O
Mol. Weight561.93 (anhydrous basis)

别名和识别编码

Chemical Name2'-(4-Ethoxyphenyl)-5-(4-Methylpiperazin-1-Yl)-1H,1'H-2,5'-Bibenzo[D]Imidazole
Synonym HOE 33342; 2'-(4'-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate
CAS Number23491-52-3
PubChem Substance ID57647173
Beilstein Registry Number1234011
MDL NumberMFCD00012678
EC Number245-691-1
Chemical Name Translation2’-(4-乙氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1’H-2,5’-联苯并[d]咪唑
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分类

  • {SNA} Alphabetical, Detection,
  • {SA} Alphabetical, Biochemicals and Reagents, Detection, Fluorescent Probes, Labels, Particles and Stains, Fluorescent Stains, Luminescent Compounds/Detection,
  • {SNA} Alphabetical, Apoptosis Detection, Apoptosis and Cell Cycle, B, Core Bioreagents, Fluorescent Stains, General Reagents, Life Science Reagents for RNAi, Nucleic Acid Stains, Reagents, Research Essentials, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 荧光探针，标记，粒子和染色剂,

相关文献及参考

  • Crissman, H.A., and Steinkamp, J.A., Exp. Cell Res. 173 , 256, (1987) 摘要
  • Latt, S.A. and Stetten, G. J. Histochem. Cytochem. 24 , 24, (1976)
  • Merck 14 ,10367

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xn
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
Precautionary statements
Signal word
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSDT4200000
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S37 Wear suitable gloves 戴适当手套；
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 umol/L
REFERENCE :
   JHCYAS Journal of Histochemistry and Cytochemistry.  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1953-
   Volume(issue)/page/year: 30,111,1982

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Fibroblast
DOSE/DURATION           : 5 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 9,485,1988

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 300 nmol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 13,2389,1992

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 umol/L
REFERENCE :
   JHCYAS Journal of Histochemistry and Cytochemistry.  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1953-
   Volume(issue)/page/year: 30,111,1982

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Luminescent Compounds/Detection - Biochemicals and Reagents
  4. Wavelength Index - Luminescent Compounds/Detection
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Chromatography Reagents & Solvents - Analytical Reagents
  4. GC Solvents - Chromatography Reagents & Solvents
  5. Purge & Trap Solvents - GC Solvents
  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Stains and Dyes - Hematology and Histology
  4. Stains & Dyes, A to Z - Stains and Dyes
  5. B - Stains & Dyes, A to Z
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Benzimidazoles 苯并咪唑
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for RNAi - Core Bioreagents
  4. General Reagents - Life Science Reagents for RNAi
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Apoptosis Detection - Apoptosis and Cell Cycle
  6. Reagents - Apoptosis Detection

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