2,6-Pyridinediamine, 3-(2-phenyldiazenyl)-, hydrochloride (1:1) 2,6-二氨基-3-苯偶氮基吡啶盐酸盐

CAS 136-40-3 MFCD00035347

化学结构图

136-40-3
SMILES: Cl.NC1=CC=C(/N=N/C2C=CC=CC=2)C(N)=N1

化学属性

Mol. FormulaC11H12ClN5
Mol. Weight250
Melting Pointca 240° dec.
TSCANo
SolubilityDMSO 50 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Density1.422
Appearance 淡红色至暗紫色结晶性粉末。

别名和识别编码

Chemical Name2,6-Pyridinediamine, 3-(2-phenyldiazenyl)-, hydrochloride (1:1)
CAS Number136-40-3
Alfabeta NamePHENYLAZODIAMINOPYRIDINEHYDROCHLORIDE 326---,
MDL NumberMFCD00035347
Synonym 2,6-Diamino-3-(phenylazo)pyridine monohydrochloride {C Pyrizin W 1655 { NCI-C01672 PHENAZOPYRIDINE HCL 3-BENZENEAZO-2,6-DIAMINOPYRIDINE MONOHYDROCHLORIDE 2,6-Diamino-3-phenylazopyridine hydrochloride 2,6-Pyridinediamine, 3-[(1E)-2-phenyldiazenyl]-, hydrochloride (1:1) Diridone Pyripyridium ######## PYRIDACIL 3-(Phenylazo)-2,6-py 3-苯偶氮基-2,6-二氨基吡啶盐酸化物 PHENYLA 非那吡啶盐 Sedural Mallofeen BISTERIL Nefrecil Phenylazo-alpha,alpha'-diaminopyridine monohydrochloride Eucistin 非那吡啶 盐酸盐 2,6-diamino-3-(phenylazo)-pyridinmonohydrochloride Phenylazodiaminopyridine hydrochloride 3-PHENYLAZO-2,6-DIAMINOP PHENAZODINE Uridina Azodyne Urobiotic-250 3-苯基偶氮-2,6-二氨基吡啶盐酸盐 Phenyl-idium 200 2,6-Diamino-3-phenylazopyridine hy Uriplex azod 3-(phenylazo)-2,6-pyridinediamine,hydrochloride 2,6-Diamino-3-(phenylazo)pyridine PYRIDIATE Phenazopyridine hydrochloride {h URODINE 3-Phenylazo-2,6-diaminopyridine hydrochloride Urazium 3-PHENYLAZO-2,6-DIAMINOPYRIDINE HYDROCHLORI 3-苯偶氮-2,6-二氨基嘧啶单盐酸化物 beta-Phenylazo-alpha,alpha'-diaminopyridine hydrochloride Phenazopyridinium chloride Phenylazopyridine hydrochloride 2,6-二氨基-3-苯偶氮基吡啶盐酸盐 2,6-DIAMINO-3-(PHENYLAZO)PYRIDINE MONOHYDROCHLORIDE {ha Pyridivite 2,6-二氨基-3-(苯偶氮基)吡啶 盐酸盐 盐酸苯偶氮吡胺 Giracid {Che NC 150 盐酸非那吡啶
PubChem Substance ID87563236
EC Number205-243-8
Beilstein Registry Number2384789
Reaxys-RN9085019
Merck Number7210
Chemical Name Translation2,6-二氨基-3-苯偶氮基吡啶盐酸盐
Wiswesser Line NotationT6NJ BZ CNUNR& FZ &GH
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分类

  • Bases & Related Reagents
  • Nucleotides
  • Heterocycles
  • Pharmaceuticals
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, P, PER - POLA
  • {SNA} Analytical Standards, Opiates / Synthetic Analgesic Drug Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
  • Aromatics
  • Intermediates & Fine Chemicals,

产品应用

  • An azo dye used in treatment of urinary tract infections. Used as an analgesic (urinary tract).

相关文献及参考

  • Becker, B.A., et al.: Toxicol. Appl. Pharmacol., 1, 42 (1959),
  • Blessel, K.W., et al.: Anal. Profiles Drug. Subs., 3, 465 (1974),
  • Shang, E., et al.: Anal. Bioanal. Chem., 382, 216 (2005),

安全信息

Warnings IRRITANT
RTECSUS7875000
GHS Symbol
Precautionary statements
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P332+P313
  • P301+P312+P330
  • P302+P350
  • P337+P313
  • P308+P313
  • P302+P352+P332+P313+P362+P364
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P305+P351+P338+P337+P313
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P302+P352
  • P405 Store locked up. 上锁保管。
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Signal word
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S22 Do not breathe dust 不要吸入粉尘；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Hazard Codes Xn
Storage condition 储存温度-20°C
UN Number 2811 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 225 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - colon tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-99,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - colon tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-99,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 81 gm/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-99,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-99,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Vascular - BP elevation not characterized in autonomic section
   Kidney, Ureter, Bladder - hematuria
   Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
   AJDCAI American Journal of Diseases of Children.  (AMA, 535 N. Dearborn St.,
   Chicago, IL 60610) V.1-80(3), 1911-50; V.100-    1960-
   Volume(issue)/page/year: 117,369,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 86 mg/kg/10D-I
TOXIC EFFECTS :
   Spinal Cord - inflammatory changes
REFERENCE :
   AIMEAS Annals of Internal Medicine.  (American College of Physicians, 4200
   Pine St., Philadelphia, PA 19104)  V.1-    1927-  Volum

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Kidney, Ureter, Bladder - urine volume decreased
   Nutritional and Gross Metabolic - changes in sodium
REFERENCE :
   AIMEAS Annals of Internal Medicine.  (American College of Physicians, 4200
   Pine St., Philadelphia, PA 19104)  V.1-    1927-  Volume(issue)/page/year:
   72,89,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
   Blood - normocytic anemia
   Nutritional and Gross Metabolic - dehydration
REFERENCE :
   CMAJAX Canadian Medical Association Journal.  (Canadian Medical Assoc., POB
   8650, Ottawa, ON K1G 0G8, Canada)  V.1-    1911-  Volume(issue)/page/year:
   91,756,1964

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 60 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 315,147,1994

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 30 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Specific locus test
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 20 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   17,196,1991

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 155 mg/kg/48H (Intermittent)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 389,3,1997

其他信息

  • TCI Shanghai:3-苯偶氮基-2,6-二氨基吡啶单盐酸盐 3-Phenylazo-2,6-diaminopyridine Monohydrochloride,>;98.0%(LC)(T)(136-40-3)
  • Sigma Aldrich:136-40-3(sigmaaldrich)
  • MSDS 信息:2,6-Diamino-3-phenylazopyridine hydrochloride(136-40-3).msds
  • Alfa Aesar:3-苯基偶氮-2,6-二氨基吡啶盐酸盐,98+% 3-Phenylazo-2,6-diaminopyridine hydrochloride, 98+%(136-40-3)
  • 2,6-DIAMINO-3-(PHENYLAZO)-PYRIDINE HYDROCHLORIDE
  • 用途一:盐酸非那吡啶【136-40-3】用于缓解由膀胱炎、前列腺炎、尿道炎、淋病性尿道炎及内窥镜检查、尿道插管等所引起的尿道及膀胱疼痛、灼热感和尿频、尿急等不适。
  • 质量标准参考:质量标准：USP30 性状：暗红色结晶性粉末 含量：99.0-101.0% 干燥失重：≤ 1.0% 炽灼残渣：≤ 0.2% 水不溶性物：≤ 0.1% 重金属：≤ 20ppm
  • 图谱信息:盐酸非那吡啶(136-40-3)质谱(MS) 盐酸非那吡啶(136-40-3)核磁图( 1 HNMR) 盐酸非那吡啶(136-40-3)红外图谱(IR1)
  • MOL 文件:136-40-3.mol
  • 盐酸非那吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B0022 3-苯偶氮基-2,6-二氨基吡啶单盐酸盐 3-Phenylazo-2,6-diaminopyridine Monohydrochloride 25G 803元 2010/05/25 B21886 3-苯基偶氮-2,6-二氨基吡啶盐酸盐, 98+% 3-Phenylazo-2,6-diaminopyridine hydrochloride, 98+% 5g 981元 2010/05/25 B21886 3-苯基偶氮-2,6-二氨基吡啶盐酸盐, 98+% 3-Phenylazo-2,6-diaminopyridine hydrochloride, 98+% 25g 3598元

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. P - Alphabetic
  5. PER - POLA - P
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. P - Alphabetic
  5. PER - POLA - P
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyridines 吡啶

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