β-Nicotinamide adenine dinucleotide phosphate sodium salt β-烟酰胺腺嘌呤二核苷酸磷酸钠盐

CAS 1184-16-3 MFCD00036973

化学结构图

1184-16-3
SMILES: NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OP(=O)(O)O)[C@@H]3O)[C@@H](O)[C@H]2O)c1.[Na+]

化学属性

Mol. FormulaC21H27N7NaO17P3
Mol. Weight765
Melting Point175-178
TSCANo
pH:A

别名和识别编码

Chemical Nameβ-Nicotinamide adenine dinucleotide phosphate sodium salt
MDL NumberMFCD00036973
CAS Number1184-16-3
Synonym β-NADP-sodium salt β-烟酰胺腺嘌呤二核苷酸磷酸 钠盐 beta-NADP monosodium salt TPN β-NADP-Na β-NADP-sodium salt Coenzyme II sodium salt NADP TPN-Na TPN Triphosphopyridine nucleotide sodium salt β-NADP-Na 氧化型辅酶II,辅酶II钠盐水合物,氧化型辅酶II,NADP单钠盐,β-NADP钠盐 NADP beta-NADP monosodium saltTriphosphopyridine nucleotide monosodium salt 三磷酸吡啶核苷酸 钠盐 beta-NADP sodium salt Triphosphopyridine nucleotide sodium salt hydrate TPN-Na β-NADP-Na β-NADP-sodium salt Coenzyme II sodium salt NADP TPN-Na TPN 三磷酸吡啶核苷酸 钠盐
PubChem Substance ID2724369
Beilstein Registry Number4779954
EC Number214-664-6
Merck Number6344
Chemical Name Translationβ-烟酰胺腺嘌呤二核苷酸磷酸钠盐
InChIKeyXJLXINKUBYWONI-UHFFFAOYSA-O
LabNetwork Molecule IDLN01740962
InChIInChI=1S/C21H28N7O17P3.Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);/q;+1/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;/m1./s1
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分类

  • {SNA} Biochemicals and Reagents, NAD(P)(H) and Analogs, NADP, Nucleosides, Nucleotides, Oligonucleotides, Single-use vials
  • {SNA} NAD(P)(H) and Analogs, NADP, Single-use vials, 核苷,核苷酸和寡核苷酸, 生化试剂

产品应用

  • β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

相关文献及参考

  • Beilstein: 26,IV,3669

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 储存温度 -20°C,充氩密封 <0°C 0-10°C
GHS Symbol
Signal word
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激

其他信息

  • 溶于水、甲醇,微溶于乙醇,实际上不溶于醚和乙酸乙酯。

系列性分类


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