Sulfamethizole 磺胺甲噻二唑

CAS 144-82-1 MFCD00053363

化学结构图

144-82-1
SMILES: Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

化学属性

Mol. FormulaC9H10N4O2S2
Mol. Weight270.33
Density1.562
Melting Point208.0 to 211.0 deg-C

别名和识别编码

Chemical NameSULFAMETHIZOLE
MDL NumberMFCD00053363
CAS Number144-82-1
Synonym 1,5-蒽二酚 2-(p-Aminobenzenesulfonamido)-5-methylt 2-(p-aminobenzenesulfonamido)-5-methylthiadiazole 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole 2-methyl-5-sulfanilamido-1,3,4-thiadiazole 2-sulfanilamido-5-methyl-1,3,4-thiadiazole 3 4-AMINO-N-[5-METHYL-1,3,4-THIADIAZOL-2-YL]-BENZENESULFONAMIDE 4-amino-n-(5-methyl-1,3,4-thiadiazol-2-yl)-benze 4-噻二唑-2-基)-1-苯磺酰胺 4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺 N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺 Sulfamethizol 4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺 N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺 Sulfamethizol Sulfamethylthiadiazole 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole 5-methyl-2-sulfanilamido-1,3,4-thiadiazole Benzenesulfonamide, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- FNA, Sulfamethizol LABOTEST-BB LT00772293 Lucosil N(sup
PubChem Substance ID5328
Beilstein Registry Number255002
EC Number205-641-1
Chemical Name Translation磺胺甲噻二唑
Reaxys-RN255002
Merck Number8916
Wiswesser Line NotationT5NN DSJ CMSWR DZ& E1
LabNetwork Molecule IDLN00192967
InChIInChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
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分类

  • {SNA} 1694 Pharmaceuticals & Personal Care Products, Additional Standards, Analytical Standards, Antibiotics Standards, Bacteriostatic, Chemical Structure, Chromatography, Clinical Standards, EPA, Method and Regulation Specific, Neats, Pharmaceuticals, Illicit Drugs & Alcohol, Principle, Sulfonamides, 分析/色谱
  • {SA} 1694 Pharmaceuticals & Pers
  • {SNA} 1694 Pharmaceuticals & Personal Care Products, Additional Standards, Analytical Standards, Antibiotics Standards, EPA, Method and Regulation Specific, Neats, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
  • {SNA} 1694 Pharmaceuticals & Personal Care Produc

相关文献及参考

  • Merck: 14,8916

安全信息

WGK Germany2
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P333+P313
  • P333+P317
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
RTECSWP0875000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xi
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
Storage condition 储存温度2-8℃ 2-8°C 2-8℃
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6000 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   ACRAAX Acta Radiologica.  (Stockholm, Sweden)  V.1-58, 1921-62.  For
   publisher information, see ACRDA8.  Volume(issue)/page/year: 37,258,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
   OH, Chemical Rubber Co., 1969  Volume(issue)/page/year: -,111,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3668 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,388,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4444 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,388,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,388,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,159,1974

其他信息

  • 磺胺甲噻二唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 S0360 磺胺甲噻二唑 Sulfamethizole 25G 900元
  • 图谱信息:磺胺甲噻二唑(144-82-1)核磁图( 1 HNMR) 磺胺甲噻二唑(144-82-1)红外图谱(IR2) 磺胺甲噻二唑(144-82-1)核磁图( 13 CNMR) 磺胺甲噻二唑(144-82-1)质谱(MS) 磺胺甲噻二唑(144-82-1)红外图谱(IR1)
  • MOL 文件:144-82-1.mol
  • TCI Shanghai:磺胺甲噻二唑 Sulfamethizole,>;98.0%(T)(144-82-1)
  • Sigma Aldrich:144-82-1(sigmaaldrich)

系列性分类


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