Pyrithioxin Dihydrochloride 吡硫醇二盐酸盐

CAS 10049-83-9 MFCD00057357

化学结构图

10049-83-9
SMILES: Cl.Cl.CC1=NC=C(CSSCC2=CN=C(C)C(O)=C2CO)C(CO)=C1O

化学属性

Mol. FormulaC16H20N2O4S2.2ClH.H2O
Mol. Weight458.43

别名和识别编码

Chemical NamePyrithioxin Dihydrochloride
MDL NumberMFCD00057357
PubChem Substance ID24898603
EC Number233-178-5
Synonym Pyritinol dihydrochloride; 3,3'-[Dithiobis(methylene)]bis[5-hydroxy-6-methyl-4-pyridinemethanol] dihydrochloride 吡硫醇 二盐酸盐 3,3'-Dithiobis(methylene)bis(5-hydroxy-6-methyl-4-pyridinemethanol) Bonifen
CAS Number10049-83-9
Chemical Name Translation吡硫醇二盐酸盐
Wiswesser Line NotationT6NJ B1 CQ D1Q E1SS1- ET6NJ B1 CQ D1Q &GH &QH
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分类

  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, P, PU - PZ

安全信息

WGK Germany2
RTECSUT4900000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 221 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TMPBAX Trudy Moskovskogo Obshchestva Ispytatelei Prirody.  Transactions of
   the Moscow Society of Naturalists.  (Moskovskoe Obshchestvo Ispytaltelei,
   Prirody, Moscow, USSR)  V.1-    1951-  Volume(issue)/page/year: 54,156,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5786 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TMPBAX Trudy Moskovskogo Obshchestva Ispytatelei Prirody.  Transactions of
   the Moscow Society of Naturalists.  (Moskovskoe Obshchestvo Ispytaltelei,
   Prirody, Moscow, USSR)  V.1-    1951-  Volume(issue)/page/year: 54,156,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3170 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 124 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   ARZNAD Arzneimittel-Fo

系列性分类


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