Fluorescein 荧光素

CAS 2321-07-5 MFCD00066735

化学结构图

2321-07-5
SMILES: O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

化学属性

Mol. FormulaC20H12O5
Mol. Weight332.31
Melting Point320
Solubility不溶

别名和识别编码

Chemical NameFluorescein
CAS Number2321-07-5
Synonym 3',6'-Fluorandiol 9-(o-Carboxyphenyl)-6-hydroxy-3-isoxanthenone 9-(o-Carboxyphenyl)-6-hydroxy-3H-xanthen-3-one Acid Yellow 73 Benzoic acid, o-(6-hydroxy-3-oxo-3H-xanthen-9-yl)- C.I. 45350 C.I. 45350 (free acid) C.I. 45350:1 Colircusi Fluoresceina D and C Yellow No. 7 D and C Yellow No. 8 D+C Yellow No. 7 Diofluor Dipotassium Salt, Fluorescein Disodium Fluorescein Disodium Salt, Fluorescein Fluor I Strip A.T. Fluor-I-Strip A.T. Fluorescein Fluorescein Dipotassium Salt Fluorescein Disodium Salt Fluorescein Monosodium Salt Fluorescein Sodium Fluorescein Sodium, Minims Fluorescein indicator {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number219-031-8
Beilstein Registry Number94324
Chemical Name Translation荧光素
Wiswesser Line NotationT C666 BO EVJ IR BVQ& MQ
Reaxys-RN94324
Merck Number4159
PubChem Substance ID16850
MDL NumberMFCD00005050
LabNetwork Molecule IDLN00192878
InChIInChI=1S/C20H12O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20/h1-10,21-22H
Canonical SMILESO=C1OC2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=CC=C5
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分类

  • {SNA} E-F, Fluorescein and Derivatives, Fluorescent Labels, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞生物学, 荧光探针,标记,粒子和染色剂, 血液学和组织学
  • {SNA} Adsorption Indicators, Detection, Indicators, Titration, Wavelength Index, 分析/色谱, 分析试剂, 发光化合物及其检测, 生化试剂, 荧光探针,标记,粒子和染色剂
  • Heterocycles
  • Pharmaceuticals
  • Fluorescent Labels & Indicators
  • Aromatics
  • Intermediates & Fine Chemicals,

产品应用

  • ########

相关文献及参考

  • Drees, B.L. et al.: J. Biol. Chem., 271, 32168 (1996); Can. Med. Assoc. J., 80, 997 (1959); Taki, M. et al.: Prot. Eng. Des. Select., 17, 119 (2004);

安全信息

Hazard Codes Xi
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Signal word Warning
RTECSLM5075000
GHS Symbol
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P330 Rinse mouth. 漱口
  • P337+P313
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4775625

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases.
   (POB 1097, Bloomfield, NJ 07003)  V.1-    1933-  Volume(issue)/page/year:
   2,257,1934

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effe

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 15 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,95,1981

Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 2-8°C, protect from light 2-8°C, stored under nitrogen

系列性分类