3-Bromo-5-methylpyridin-2-amine 2-氨基-3-溴-5-甲基吡啶

CAS 17282-00-7 MFCD00068231

化学结构图

17282-00-7
SMILES: Cc1cnc(N)c(Br)c1

化学属性

Mol. FormulaC6H7BrN2
Mol. Weight187.04
Melting Point73-76°C
TSCANo
Density1.422
Solubility不溶
Boiling Point252.3°C at 760 mmHg

别名和识别编码

Chemical Name3-Bromo-5-methylpyridin-2-amine
CAS Number17282-00-7
Alfabeta NameAMINOBROMOMETHYLPYRIDINE 235-----
MDL NumberMFCD00068231
Synonym 3-Bromo-5-methylpyridin-2-amine {LY} 3-Bromo-5-methylpyridin-2-amine {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2-amine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Bromo-5-methylpyridin-2
PubChem Substance ID87563001
Beilstein Registry Number471829
EC Number250-023-7
Reaxys-RN471829
Chemical Name Translation2-氨基-3-溴-5-甲基吡啶
Canonical SMILESNC(C(Br)=C1)=NC=C1C
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分类

  • Heterocycles
  • Amines
  • {SNA} Building Blocks, C6, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyridines

产品应用

  • Used for the preparation of imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrazines, imidazo[1,2-c]pyrimidines, and imidazo[1,2-d]triazines as JNK and ERK kinase inhibitors

相关文献及参考

  • Lawrence, D., et al.: J. Med. Chem., 44, 594 (2001),
  • Urquiola, C., et al.: Bioorg. Med. Chem., 17, 1623 (2009),

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xn Xi
Storage condition 2-8°C {LY} 2-8°C 2-8°C, protect from light {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Chromatography Reagents & Solvents - Analytical Reagents
  4. LC-NMR Solvents (CHROMASOLV®) - Chromatography Reagents & Solvents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Halogenated 卤化物 (氟氯溴碘)
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Pyridines - Halogenated Heterocycles
  1. C6 to C7 - Pyridines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Pyridazines
  1. C5
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Pyridines 吡啶

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