(2R,3R,4S,5R)-2-(2-Chloro-6-(Cyclopentylamino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol (2R,3R,4S,5R)-2-(2-氯-6-(环戊基氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇

CAS 37739-05-2 MFCD00078574

化学结构图

37739-05-2
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=C(Cl)N=C2NC1CCCC1

化学属性

Mol. FormulaC15H20ClN5O4
Mol. Weight369.80

别名和识别编码

Chemical Name(2R,3R,4S,5R)-2-(2-Chloro-6-(Cyclopentylamino)-9H-Purin-9-Yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol
CAS Number37739-05-2
Synonym 2-Chloro-N-cyclopentyladenosine 2-Chloro-N6-cyclopentyladenosine CCPA
MDL NumberMFCD00078574
PubChem Substance ID24892583
Chemical Name Translation(2R,3R,4S,5R)-2-(2-氯-6-(环戊基氨基)-9H-嘌呤-9-基)-5-(羟甲基)四氢呋喃-3,4-二醇
Beilstein Registry Number4888162
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分类

  • Bases & Related Reagents
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cell Biology, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides
  • {SNA} Nucleoside Analogs, 核苷，核苷酸和寡核苷酸, 生化试剂
  • Nucleotides
  • Carbohydrates & Derivatives
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • ########

相关文献及参考

  • Arch, J., et al.: Biochem. J., 174, 965 (1978),
  • Agnati, L., et al.: Pharmacol. Rev., 55, 509 (2003),
  • Badman, M., et al.: Science, 307, 1909 (2005),

安全信息

WGK Germany3
RTECSAU7357555
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1305,1994

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Synthetic Oligonucleotides and Related Reagents - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. C-CH - Bioactive Small Molecules

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