BUTIROSIN A
CAS 34291-02-6 MFCD00078992
化学结构图
SMILES: N[C@H]1C[C@@H](NC(=O)[C@@H](O)CCN)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H]2O)[C@@H]1O[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1N
化学属性
| Mol. Formula | C21H41N5O12 |
|---|---|
| Mol. Weight | 555.67 |
别名和识别编码
| Chemical Name | D-Streptamine,O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D- xylofuranosyl-(1-5))-N(sup1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy- |
|---|---|
| MDL Number | MFCD00078992 |
| PubChem Substance ID | 24892143 |
| Wiswesser Line Notation | T6OTJ B1Z CQ DQ EZ FO- BL6TJ AZ DQ EMVYQ2Z CO- BT5OTJCQ DQ E1Q |
| Synonym | Butirosin A Butyrosin A Ambuyrosin A Ambutyrosin A |
| CAS Number | 34291-02-6 |
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分类
- {SNA} Aminoglycosides, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Chemical Structure Class, Genetic Marker Selection, Interferes with Protein Synthesis, Mechanism of Action
安全信息
GHS Symbol
- P308+P313
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- H332 Harmful if inhaled 吸入有害
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2198 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,145,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 580 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,239,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3050 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,145,1980
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