Famprofazone

CAS 22881-35-2 MFCD00079304

化学结构图

22881-35-2
SMILES: CC(C)C1C(=O)N(C2C=CC=CC=2)N(C)C=1CN(C)C(C)CC1C=CC=CC=1

化学属性

Mol. FormulaC24H31N3O
Mol. Weight377.58

别名和识别编码

Chemical NamePyrazolin-5-one,4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-
CAS Number22881-35-2
Synonym Antipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))- 1,2-Dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-3H-pyrazol-3-one 泛普法宗 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine
MDL NumberMFCD00079304
PubChem Substance ID24894971
EC Number245-284-9
Wiswesser Line NotationT5NNVJ A1 BR& DY1&1 E1N1&Y1&1R
Beilstein Registry Number5768367
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SA} All Doping Standards (A-Z), Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Doping Substances, Drugs & Metabolites, F, FA - FL, Forensic and Veterinary Standards, Neat Compounds, Non-Specified Stimulant, Stimulans
  • {SNA} Alphabetical Index of Analytical Standards, All Doping Standards (A-Z), Analytical Standards, Analytical/Chromatography, Chromatography, Doping Substances, Drugs & Metabolites, F, FA - FL, Forensic and Veterinary Standards, Neat Compounds,

产品应用

  • Famprofazone, which is known to metabolize to Methamphetamine (M258795) and Amphetamine (A634248) and is included in the prohibited list of the World Anti-Doping Agency.

相关文献及参考

  • Oh, E., et al.: Xenobiotica, 22, 377 (1992),
  • Greenhill, B., et al.: J. Anal. Toxicol., 27, 479 (2003),
  • Tseng, Y.L., et al.: J. Forensic Sci., 52, 479 (2007),

安全信息

RTECSUQ9451000
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SMWOAS Schweizerische Medizinische Wochenschrift.  (Schwabe & Co.,
   Steintorst 13, 4010 Basel, Switzerland)  V.50-    1920-
   Volume(issue)/page/year: 84,351,1954

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. F - Alphabetic
  5. FA - FL - F
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Forensic and Veterinary Standards - Chromatography
  5. Doping Substances - Forensic and Veterinary Standards
  6. All Doping Standards (A-Z) - Doping Substances

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