Sauvagine
CAS 74434-59-6 MFCD00081983
化学结构图
SMILES: [H]/N=C(\N)/NCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN/C(/N)=N/[H])NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O
化学属性
| Mol. Weight | 4599.31 |
|---|---|
| Mol. Formula | C202H346N56O63S |
别名和识别编码
| MDL Number | MFCD00081983 |
|---|---|
| CAS Number | 74434-59-6 |
| Chemical Name | Sauvagine |
| Synonym | Sauvagine |
| Chemical Name Translation | |
| InChIKey | ILCVKEBXPLEGOY-ZLFMSJRASA-N |
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分类
- Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience,
- {SNA} CRF, Neuropeptides, Other Releasing Factors, Parathyroid Hormone Fragments, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small M
相关文献及参考
- [2]. P C Montecucchi, et al. Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvagei. Int J Pept Protein Res. 1981 Aug;18(2):113-20.
- [3]. M H Perrin, et al. Corticotropin releasing factor receptors and their ligand family. Ann N Y Acad Sci. 1999 Oct 20;885:312-28.
- Eckart, K., et al., Actions of CRF and its analogs. Curr. Med. Chem. 6 , 1035-1053, (1999) 摘要
- Kosoyan, H.P., et al., Intracisternal sauvagine is more potent than corticotropin-releasing factor to decrease gastric vagal efferent activity in rats. Peptides 20 , 851-858, (1999) 摘要
- Renda, T., et al., Brain-gut-skin peptides: an update overview. Arch. Histol. Cytol. , 317-323, (1989) 摘要
- [1]. David A Lovejoy, e
- [1]. David A Lovejoy, et al. Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides: expansion and specialization in the vertebrates. J Chem Neuroanat. 2013 Dec;54:50-6.
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