(+)-MK 801 MALEATE
CAS 77086-19-2 MFCD00082466
化学结构图
SMILES: C[C@@]12N[C@@H](CC3C=CC=CC1=3)C1C=CC=CC2=1.OC(=O)/C=C\C(O)=O
化学属性
| Mol. Formula | C16H15N · C4H4O4 |
|---|---|
| Mol. Weight | 337.37 |
别名和识别编码
| Chemical Name | (-)-MK-801 hydrogen maleate |
|---|---|
| Synonym | (5R,10S)-(–)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate |
| MDL Number | MFCD00082466 |
| PubChem Substance ID | 24277961 |
| CAS Number | 77086-19-2 |
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分类
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory A
- Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, M, NMDA Antagonists, Neuroscience, Neurotransmission, Neurotransmitters
- {SNA} Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, Ligand-Gated Ion Channels, NMDA Antagonists, Neuroscience, Neurotransmission, Neurotransmitters, 细胞信号转导和神经科学,
相关文献及参考
- Wong, E.H.F., et al., The anticonvulsant MK-801 is a potent NMDA antagonist. Proc. Natl. Acad. Sci. U. S. A. 83 , 7104-7108, (1986) 摘要
- Griesbach, G.S., et al., Immediate and long-term effects of neonatal MK-801 treatment on nonspatial learning. Proc. Natl. Acad. Sci. U. S. A. 95 , 11435-11439, (1998) 摘要
- Ma, J., et al., Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice. Br. J. Pharmacol. 124 , 756-762, (1998) 摘要
- Merck 14 ,3386
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