L-(+)-2-Amino-4-phosphonobutyric acid
CAS 23052-81-5 MFCD00083244
化学结构图
SMILES: N[C@@H](CCP(O)(O)=O)C(O)=O
化学属性
| Mol. Formula | C4H10NO5P |
|---|---|
| Mol. Weight | 183.10 |
| TSCA | No |
别名和识别编码
| Chemical Name | L-(+)-2-Amino-4-phosphonobutyric acid |
|---|---|
| Synonym | L-(+)-2-Amino-4-phosphonobutyric acid L-AP-4 L-AP-4 L-AP4 |
| MDL Number | MFCD00083244 |
| PubChem Substance ID | 24891296 |
| CAS Number | 23052-81-5 |
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分类
- {SNA} A-AM, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Metabotropic Agonists, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
- {SNA} Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Metabotropic Agonists, Neuroscience, Neurotransmission, Neur
相关文献及参考
- [2]. Chen SR, et al. Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats. J Pharmacol Exp Ther. 2005 Jan;312(1):120-6.
- [1]. Selvam C, et al. Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites. J Med Chem. 2018 Mar 8;61(5):1969-1989.
- [1]. Selvam C, et al. Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites. J Med Chem. 2018 Mar 8;61(5):1969-1989.
- [2]. Chen SR, et al. Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats. J Pharmacol Exp Ther. 2005 Jan;312(1):120-6.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- S37 Wear suitable gloves 戴适当手套；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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