Leucomycin V 柱晶白霉素水合物, ≥1300单位/毫克
CAS 1392-21-8 MFCD00147435
化学结构图
SMILES: COC1C(O)CC(=O)OC(C)CC=CC=CC(O)C(C)CC(CC=O)C1OC1OC(C)C(OC2CC(C)(O)C(O)C(C)O2)C(N(C)C)C1O
化学属性
| Mol. Formula | N/A |
|---|---|
| Mol. Weight | 540.70 |
| Density | 1.25 |
别名和识别编码
| MDL Number | MFCD00147435 |
|---|---|
| Chemical Name | Leucomycins (>85%) |
| Synonym | A 6599 Ayermicina C 637 Kitasamycin Leucomycin Selectomycin Stereomycine Syneptine turimycin 柱晶白霉素 柱晶白霉素 水合物 |
| CAS Number | 1392-21-8 |
| Chemical Name Translation | 柱晶白霉素水合物, ≥1300单位/毫克 |
| PubChem Substance ID | 5282189 |
| InChI | InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1 |
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分类
- {SNA} Analytical Standards, Analytical/Chromatography, Antibiotics, Chemical Structure, Chromatography, Clinical Standards, Others
产品应用
- 治畜禽呼吸道疾病。与红霉素相似。对革兰阳性菌和霉形体有较强抗菌作用，对部分革兰阴性菌、钩端螺旋体、立克次及衣原体也有效。小剂量作猪、鸡饲料添加剂，具有促进生长作用。主要用于百日咳、肺炎、支气管炎、扁桃体炎、中耳炎、淋病、淋病性尿路炎等病症的治疗。
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3000 ku/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (E
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Be
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 650 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 6,87,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1758 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,354,1995
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >7500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,354,1995
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