Imetit Dihydrobromide IMETIT氢溴酸盐

CAS 32385-58-3 MFCD00153816

化学结构图

32385-58-3
SMILES:

化学属性

Mol. FormulaC6H10N4S · 2HBr
Mol. Weight332.06

别名和识别编码

Chemical NameImetit Dihydrobromide
Synonym Imetit dihydrobromide S-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide
MDL NumberMFCD00153816
PubChem Substance ID24277783
Chemical Name TranslationIMETIT氢溴酸盐
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分类

  • {SNA} Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, I, Membrane Protein Biology Tools, Mistaminergics - Agonists, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
  • {SNA} Agonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, I, Membrane Protein Biology Tools, Mistaminergics - Agonists, Neuroscience, Ne

相关文献及参考

  • [2]. Ling P, et al. Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation. Br J Pharmacol. 2004 May;142(1):161-71.
  • [3]. Garbarg M, et al. S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist. J Pharmacol Exp Ther. 1992 Oct;263(1):304-10.
  • [4]. Farzin D, et al. Influence of different histamine receptor agonists and antagonists on apomorphine-induced licking behavior in rat. Eur J Pharmacol. 2000 Sep 15;404(1-2):169-74.
  • [1]. Liu C, et al. Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol. 2001 Mar;59(3):420-6.
  • [1]. Liu C, et al. Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol. 2001 Mar;59(3):420-6.
  • [2]. Ling P, et al. Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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