Potassium O-((4R,7R)-octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate O-((4R,7R)-八氢-1H-4,7-甲茚-5-基)碳二硫代钾

CAS 83373-60-8 MFCD00171401

化学结构图

83373-60-8
SMILES: S=C(OC1C[C@@H]2C[C@H]1C1CCCC21)S[K] |&1:5,7|

化学属性

Mol. FormulaC11H15KOS2
Mol. Weight266.46
Density1.422

别名和识别编码

Chemical NamePotassium O-((4R,7R)-octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate
Synonym D609
MDL NumberMFCD00171401
PubChem Substance ID24278031
CAS Number83373-60-8
EC Number280-379-9
Beilstein Registry Number2384789
Chemical Name TranslationO-((4R,7R)-八氢-1H-4,7-甲茚-5-基)碳二硫代钾
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Lipids in Cell Signaling, P to Q, Phospholipase C, phosphatidylcholine-specific, Phospholipase Inhibitors, Phospholipid Metabolism, T, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • {SA} Bioactive Small Molecules,
  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Lipids in Cell Signaling, P to Q,

相关文献及参考

  • [2]. Milhas D, et al. The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes.Int J Mol Sci. 2012;13(7):8834-52. Epub 2012 Jul 16.
  • [3]. Gusain A, et al. Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition.Mol Neurobiol. 2012 Jun;45(3):455-64. Epub 2012 Mar 14.
  • Grates, et al., Inhibition of phospholipase D by agents that inhibit cell growth. Anticancer Res. 13 , 1239-1244, (1993) 摘要
  • Mellert, W., et al., Inhibition of HIV-1 replication by an antiviral xanthate compound in vitro. . AIDS Res. Hum. Retroviruses 4 , 71, (1988) 摘要
  • Muller-Decker, K., Interpretation of TPA-induced signals by an antiviral and antitumoral xanthate compound: Inhibition of a phospholipase C-type reaction. Biochem. Biophys. Res. Commun. 162 , 198, (1989) 摘要
  • [1]. Kalluri HS, et al. D609 inhibits the pro

安全信息

GHS Symbol
Signal word
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements

系列性分类


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