(R)-(+)-4-Hydroxy-2-Pyrrolidinone (R)-4-羟基-2-吡咯酮

CAS 22677-21-0 MFCD00273364

化学结构图

22677-21-0
SMILES: O[C@@H]1CNC(=O)C1 |&1:1|

化学属性

Mol. FormulaC4H7NO2
Mol. Weight101
Melting Point156-159

别名和识别编码

Chemical Name(R)-(+)-4-Hydroxy-2-Pyrrolidinone
CAS Number22677-21-0
Alfabeta NameHYDROXYPYRROLIDONE R42()----
MDL NumberMFCD00273364
Synonym (4R)-4-Hydroxy-2-pyrrolidinone (R)-4-Hydroxypyrrolidin-2-one (R)-(+)-4-羟基-2-吡咯烷酮 (R)-β-羟基-γ-丁内酰胺 (R)-β-羟基-γ-丁内酰胺 (R)--Hydroxy--butyrolactam (4R)-4-Hydroxypyrrolidin-2-one (R)-β-羟基-γ-丁内酰胺 (R)-4-Hydroxy-2-pyrrolidinone (R)-4-hydroxy-2-pyrrolidinone
PubChem Substance ID24871603
Beilstein Registry Number1524193
Chemical Name Translation(R)-4-羟基-2-吡咯酮
LabNetwork Molecule IDLN00009521
InChIKeyIOGISYQVOGVIEU-GSVOUGTGSA-N
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分类

  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Pyrrolidines
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Amines

产品应用

  • The (R)-enantiomer intermediate in the preparation of Oxiracetam

相关文献及参考

  • Di Silvestro, G., et al.: J. Pharm. Sci., 82, 758 (1993),
  • Kondepudi, D., et al.: Science, 250 975 (1990),

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Heterocyclic Building Blocks - Chiral Building Blocks
  5. Pyrrolidines - Heterocyclic Building Blocks

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