Desogestrel 去氧孕烯

CAS 54024-22-5 MFCD00869346

化学结构图

54024-22-5
SMILES: CC[C@]12CC(=C)[C@@H]3[C@H]4CCCC=C4CC[C@H]3[C@@H]1CC[C@@]2(O)C#C

化学属性

Mol. FormulaC22H30O
Mol. Weight310.48
Melting Point110-114

别名和识别编码

Chemical NameDesogestrel
CAS Number54024-22-5
Synonym (17?)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol 13-Ethyl-11-methylene-18,19-dinor-17-4-pregnen-20-yn-17-ol 13-Ethyl-11-methylene-18,19-dinor-17-alpha-pregn-4-en-20-yn-17-ol 13-​Ethyl-​11-​methylene-​18,19-​dinor-​17α-4-pregnen-20-yn-17-ol 13-乙基-11-亚甲基-18,19-双失碳孕甾-4-烯-20-炔基-17-醇 Cerazette Cyclosa Desogestrel Marvelon 150/320 ORG 2969 Org 2969
MDL NumberMFCD00869346
EC Number258-929-4
Chemical Name Translation去氧孕烯
Reaxys-RN5094648
PubChem Substance ID135727366
Merck Number2926
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分类

  • Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Clinical Standards, D, DA - DH, Hormones, Market Segments, Neats and Solutions, Standards for Food and Beverage Analysis, Standards for Pharma Clinical Forensic & Veterinary Analysis
  • {SNA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Clinical Standards, D, DA - DH, Hormones, Market Segments, Neats and Solutions, Standards for Food and Beverage Analysis, Standards for Pharma Clinical Forensic & Veterinary Analysis

产品应用

  • A progestogen with low androgenic potency.

相关文献及参考

  • Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979),
  • Merck 14 ,2926

安全信息

GHS Symbol
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSJF7975000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 24 ug/kg
SEX/DURATION            : female 20 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ACENA7 Acta Endocrinologica (Copenhagen).  (Periodica, Skolegade 12 E,
   DK-2500 Valby, Denmark) V.1-    1948-  Volume(issue)/page/year: 83,429,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 6 ug/kg
SEX/DURATION            : female 20 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertilit

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6250 ug/kg
SEX/DURATION            : female 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,231,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 125 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,231,1983

UN Number 3077
Hazard Codes 9
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Packing GroupIII

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Market Segments - Analytical Standards
  4. Standards for Pharma Clinical Forensic & Veterinary Analysis - Market Segments
  5. Neats and Solutions - Standards for Pharma Clinical Forensic & Veterinary Analysis
  6. Hormones - Neats and Solutions

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