(4-Fluorostyryl)Boronic Acid (4-氟苯乙烯基)硼酸

CAS 214907-24-1 MFCD02093725

化学结构图

214907-24-1
SMILES: OB(O)/C=C/C1C=CC(F)=CC=1

化学属性

Mol. FormulaFC6H4CH=CHB(OH)2
Mol. Weight165.96
Melting Point182-186 °C (lit.)

别名和识别编码

Chemical Name(4-Fluorostyryl)Boronic Acid
CAS Number214907-24-1
Alfabeta NameFLUOROPHENYLVINYLBORONICACID TRANS24()---
MDL NumberMFCD02093725
PubChem Substance ID24874056
Synonym TRANS-2-(4-FLUOROPHENYL)VINYLBORONIC ACID 反式-2-(4-氟苯基)乙烯基硼酸
Chemical Name Translation(4-氟苯乙烯基)硼酸
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分类

  • {SNA} Alkenyl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Organometallic Reagents
  • Alkenyl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Organometallic Reagents

相关文献及参考

  • 1. Thornton, P. D.; et al., Application of 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Suzuki-Miyaura and Buchwald-Hartwig Cross-Coupling Reactions for the Preparation of Annulated Indole Libraries ACS Comb. Sci. 13 , 443-448, (2011)
  • 2. De Simone, R.; et al., Toward the discovery of new agents able to inhibit the expression of microsomal prostaglandin E synthase-1 enzyme as promising tools in drug development Chem. Biol. Drug Des. 76 , 17-24, (2010)
  • 3. Hollick, J. J.; et al., Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol 3-Kinase Related Kinases. Structure-Activity Relationships for DNA-Dependent Protein Kinase Inhibition, and Identification of the First Potent and Selective Inhibitor of the Ataxia Telangiectasia Mutated Kinase J. Med. Chem. 50 , 1958-1972, (2007)
  • 4. de la Herran, G.; Csaky, A. G. , 1,6-Conjugate addition of boronic acids to 2-allylidenemalonates Synlett , 585-588, (2009)

安全信息

Warnings IRRITANT
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard Codes Xi

其他信息

  • Hazard Note:Irritant
  • Sigma Aldrich:214907-24-1(sigmaaldrich)
  • MOL 文件:214907-24-1.mol

系列性分类


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