(3β,24S)-Cholest-5-ene-3,24-dio… (3β，24S） - 胆甾-5 - 烯-3,24-二醇

CAS 474-73-7 MFCD03695560

化学结构图

474-73-7
SMILES: CC(C)[C@@H](O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C

化学属性

Mol. FormulaC27H46O2
Mol. Weight403

别名和识别编码

Chemical Name(3β,24S)-Cholest-5-ene-3,24-dio…
Synonym 24(S)-hydroxycholesterol (3β,24S)-Cholest-5-ene-3,24-diol
MDL NumberMFCD03695560
CAS Number474-73-7
Chemical Name Translation(3β，24S） - 胆甾-5 - 烯-3,24-二醇
LabNetwork Molecule IDLN01265570
PubChem Substance ID121948
InChIInChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
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相关文献及参考

  • [2]. M Shafaati, et al. Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J Intern Med. 2011 Oct;270(4):377-87.
  • [3]. Steven M Paul, et al. The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors. J Neurosci. 2013 Oct 30;33(44):17290-300.
  • [1]. Yuki Kimura, et al. Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation. Biochimie. 2018 Oct;153:203-209.
  • [1]. Yuki Kimura, et al. Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation. Biochimie. 2018 Oct;153:203-209.
  • [2]. M Shafaati, et al. Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J Intern Med. 2011 Oct;270(4):377-87.
  • [3]. Steven M Paul, et al. The major brain cholesterol metabolite 24

安全信息

WGK Germany3

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. LXR  (肝X受体)
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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