OCTANOYL COENZYME A LITHIUM SALT HYDRATE

CAS 324518-20-9 MFCD10567452

化学结构图

324518-20-9
SMILES: [Li+].O.CCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])(O)=O)N1C=NC2C(N)=NC=NC1=2

化学属性

Mol. FormulaC29H50N7O17P3S · xLi+· yH2O
Mol. Weight893.73 (free acid basis)

别名和识别编码

Chemical NameOctanoyl coenzyme A lithium salt hydrate
Synonym Capryloyl coenzyme A lithium salt hydrate
PubChem Substance ID24898040
CAS Number324518-20-9 (anhydrous)
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分类

  • {SNA} Coenzyme A and Other Acyl Transfer Reagents, Cofactors, Fatty Acyls, Fatty Esters, Fatty acyl CoAs, Lipid, Lipid Library Collection, Metabolite Libraries and Collections, 代谢组学, 代谢通路,
  • Biochemicals and Reagents, Coenzyme A and Other Acyl Transfer Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Fatty Acid Metabolism, Fatty Acyls, Fatty Esters, Fatty acyl CoAs, Lipid, Lipid Library, Lipids, Metabolic Libraries, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics
  • {SNA} Coe

相关文献及参考

  • Yang J, Brown MS, Liang G, et al., Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132 , 387-396, (2008) 摘要
  • Gutierrez JA, Solenberg PJ, Perkins DR, et al., Ghrelin octanoylation mediated by an orphan lipid transferase. Proc. Natl. Acad. Sci. U. S. A. 105 , 6320-6325, (2008) 摘要
  • Takahashi T, Ida T, Sato T, et al., Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid. J. Biochem. 146 , 675-682, (2009) 摘要
  • Ohgusu H, Shirouzu K, Nakamura Y, et al., Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. Biochem. Biophys. Res. Commun. 386 , 153-158, (2009) 摘要
  • Romero A, Kirchner H, Heppner K, et al., GOAT: the master switch for the ghrelin system? Eur. J. Endocrinol. 163 , 1-8, (2010) 摘要
  • Lim CT, Kola B, Grossman A, Korbonits M., The expression of ghrelin O-acyltransferase (GOAT) in human tissues. Endocrine J. 58 , 707-710, (2011)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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