RG-239 hydrate

CAS N/A MFCD17215967

化学结构图

N/A
SMILES:

化学属性

Mol. Weight496.76 (anhydrous basis)
Mol. FormulaC33H52O3· xH2O

别名和识别编码

Synonym (3)-3-Hydroxy-3-(2-propen-1-yl)-lup-20(29)-en-28-oic acid hydrate (3)-3-Hydroxy-3-(2-propen-1-yl)-lup-20(29)-en-28-oic acid hydrate (3R)-3-Allyl-3-hydroxylup-20(29)-en-28-oic acid hydrate 18 dia 2 (3?)-3-Hydroxy-3-(2-propen-1-yl)-lup-20(29)-en-28-oic acid hydrate (3R)-3-Allyl-3-hydroxylup-20(29)-en-28-oic acid hydrate 18 dia 2
MDL NumberMFCD17215967
Chemical NameRG-239 hydrate
PubChem Substance ID329823992
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Other Steroid Products, R, Steroid Hormones
  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, Hormones, Other Steroid Products, R,

相关文献及参考

  • Genet, C., et al, Structure-Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes. J. Med. Chem. 53 , 178-190, (2010)
  • Pellicciari, R., et al, Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5. J. Med. Chem. 50 , 4265-4268, (2007)
  • Thomas, C., et al., TGR5-mediated bile acid sensing controls glucose homeostasis Cell Metab. 10 , 163-177, (2009) 摘要

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P301+P312+P330
  • P301+P310
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
Signal word Danger Warning
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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