Cerivastatin sodium

CAS 143201-11-0 MFCD43201110

化学结构图

143201-11-0
SMILES: COCc1c(C(C)C)nc(C(C)C)c(C=CC(O)CC(O)CC(=O)[O-])c1-c1ccc(F)cc1.[Na+]

化学属性

Mol. Weight481.53
Mol. FormulaC26H33FNNaO5

别名和识别编码

CAS Number143201-11-0
Chemical NameCerivastatin
Synonym (3R,5S,6E)-7-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt 6-Heptenoic acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, monosodium salt, (S-(R*,S*-(E)))- 7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyrid-3-yl)-3,5-dihydroxy-6-heptenoate sodium salt Bay w 6228 Baycol Certa Kazak Lipobay Rivastatin, Baycol, Lipobay cerivastatin cerivastatin sodium rivastatin
PubChem Substance ID23663992
InChIInChI=1S/C26H34FNO5.Na/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4;/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32);/q;+1/p-1/b11-10+;/t19-,20-;/m1./s1
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Inhibitors,

产品应用

  • A competitive inhibitor of HMG-CoA reductase.

相关文献及参考

  • Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996),
  • Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996),

系列性分类

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