5-Ethyl-2-Methylpyridine 5-乙基-2-甲基吡啶

CAS 104-90-5 MFCD00006344

化学结构图

104-90-5
SMILES: CCc1ccc(C)nc1

化学属性

Mol. FormulaC₈H₁₁N
Mol. Weight121.18
Density0.919 g/mL at 25 °C(lit.)
Refractive index1.4970 to 1.4990
Vapor Density4.2 (vs air)
Boiling Point-
Flash Point-
TSCAYes
Melting PointN/A
Solubility不溶于水,溶于乙醇、乙醚、苯、稀酸。

别名和识别编码

Chemical Name5-Ethyl-2-Methylpyridine
CAS Number104-90-5
Synonym 2,5-Aldehydine 2-METHYL-5-ETHYLPYRIDINE 2-Methyl-5-Ethylyridine 2-Methyl-5-ethylpyridine 2-Methyl-5-ethylpyridine; 5-Ethyl-2-picoline 2-Methyl-5-äthylpyridin 2-Picoline, 5-ethyl- 2-甲基-5-乙基吡啶 3-ETHYL-6-METHYLPYRIDINE 3-Ethyl-6-methylpyridine 3-乙基-6-甲基吡啶 5-ETHYL-2-METHYLPYRIDINE 5-ETHYL-2-METHYLPYRIDINE 97+% 5-ETHYL-2-PICOLINE 5-Ethyl-2-methylpyridine 5-Ethyl-2-picoline 5-Ethyl-alpha-picoline 5-Ethyl-α-picoline 5-ethyl-2-methyl-pyridin 5-ethyl-2-methyl-pyridine 5-ethyl-2-methylpyridine 5-ethyl-2-picolin 5-ethyl-2-picoline 5-​Ethyl-​2-​methylpyridine(5-Ethyl-2-picoline) {} {} {} {} {} {} {} {} {
EC Number203-250-0
Beilstein Registry Number20,248
MDL Number-
PubChem Substance ID87569437
Merck Number3844
Reaxys-RN109269
Chemical Name Translation5-乙基-2-甲基吡啶
InChIKeyNTSLROIKFLNUIJ-UHFFFAOYSA-N
Wiswesser Line NotationT6NJ B1 E2
LabNetwork Molecule IDLN00223743
InChIInChI=1S/C8H11N/c1-3-8-5-4-7(2)9-6-8/h4-6H,3H2,1-2H3
Canonical SMILES-
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分类

  • {SNA} Alphabetical Listings, E-F, Flavors and Fragrances
  • Aromatics
  • Heterocycles
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SA} Building Blocks, C8, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

产品应用

  • Perfume composition

相关文献及参考

  • Hansen, B., et al.: Environ. Toxicol. Chem., 18, 772 (1999),
  • Short: IV/18A
  • Short: IV/3
  • Merck:14,3844 Beilstein:20,248
  • Merck:14,3844
  • Short: III/38B
  • Short: IV/18B

安全信息

Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R52/53
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P308+P313
  • P403+P233
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P330+P331+P310
  • P303+P361+P353
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P370+P378
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P304+P340+P311
  • P301+P330+P331
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P304+P340+P312
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H302 Harmful if swallowed 吞食有害
  • H311+H331
  • H301+H331
  • H227 Combustible liquid 可燃液体
RTECSTJ6825000
Packing GroupIII
UN Number 2300 UN 2300 6.1/PG 3 UN2300
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes C C,N
Hazard Class6.1
Storage condition 4°C 密封阴凉保存
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 294 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,83,1982

{

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 4,119,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,846,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 282 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,83,1982

TYPE OF TEST

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 1500 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 163,23,1986

Restrict 危险品

其他信息

  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食品中文名称 添加剂功能 最大允许使用量(g/kg) 最大允许残留量(g/kg) 5-乙基-2-甲基吡啶 食品 食品用香料 用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
  • FEMA:3546
  • 灭火剂:干粉、二氧化碳、砂土、泡沫
  • 图谱信息:5-乙基-2-甲基-吡啶(104-90-5)核磁图( 13 CNMR) 5-乙基-2-甲基-吡啶(104-90-5)红外图谱(IR2) 5-乙基-2-甲基-吡啶(104-90-5)红外图谱(IR1) 5-乙基-2-甲基-吡啶(104-90-5)质谱(MS)
  • 急性毒性:口服-大鼠 LD50: 368 毫克/公斤; 口服-小鼠 LD50: 282 毫克/公斤
  • 5-乙基-2-甲基-吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 E0142 5-乙基-2-甲基吡啶 5-Ethyl-2-methylpyridine 500ML 364元 2014/06/02 E0142 5-乙基-2-甲基吡啶 5-Ethyl-2-methylpyridine 25ML 137元 2010/06/21 133950010 5-乙基-2-甲基-吡啶 5-Ethyl-2-methylpyridine 98% 1 KG 700元
  • Acros Organics:5-乙基-2-甲基-吡啶 5-Ethyl-2-methylpyridine, 98%(104-90-5)
  • MOL 文件:104-90-5.mol
  • TCI Shanghai:5-乙基-2-甲基吡啶 5-Ethyl-2-picoline,>;95.0%(GC)(104-90-5)
  • 类别:有毒物品
  • 蒸气密度:4.2 (vs air)
  • 用途二:医药中间体。
  • MSDS 信息:5-乙基-2-甲基吡啶(104-90-5).msds
  • 实际上不溶于水,溶于稀酸和浓硫酸,和常规有机溶剂混溶,溶于乙醇、乙醚和苯。
  • 外观性质:无色液体,有刺激性气味。
  • 用途一:用于医药工业,用于制备烟酸、烟酰胺、异烟肼、尼可杀米等
  • 可燃性危险特性:明火可燃; 受热分解有毒氧化氮气体
  • Alfa Aesar:5-乙基-2-甲基吡啶,98% 5-Ethyl-2-methylpyridine, 98%(104-90-5)
  • Hazard Note:Corrosive
  • 下游产品:2-甲基吡啶 --> 1-四氢萘酮 --> 5-乙基吡啶-2-羧酸 --> 2-氨基-4-苯基吡啶 --> 5-乙基-2-吡啶乙醇
  • 毒性分级:高毒
  • Sigma Aldrich:104-90-5(sigmaaldrich)
  • 刺激数据:皮肤-兔子 10 毫克/24小时 重度; 眼睛-兔子 0.25 毫克 重度
  • 储运特性:库房通风低温干燥; 与食品原料、纺织品类分开储运

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