Ambutonium Bromide
CAS 115-51-5 MFCD00865179
化学结构图
SMILES: CC[N+](C)(C)CCC(C(N)=O)(c1ccccc1)c1ccccc1.[Br-]
化学属性
| Mol. Formula | C20H27N2O.Br |
|---|---|
| Mol. Weight | 391.40 |
别名和识别编码
| Chemical Name | Ammonium,(3-carbamoyl-3,3-diphenylpropyl)dimethylethyl-,bromide |
|---|---|
| CAS Number | 115-51-5 |
| Synonym | R 100 4-Dimethylamino-2,2-diphenylbutyramide ethyl bromide Ambutonium bromide Aludrox SA (3-Carbamoyl-3,3-diphenylpropyl)dimethylethylammonium bromide BL 700 ?-(?minocarbonyl)-N-ethyl-N,N-dimethyl-?-phenylbenzenepropanaminium Bromide gamma-(Aminocarbonyl)-N-ethyl-N,N-dimethyl-gamma-phenylbenzenepropanaminium bromide BL 700 B 3-(Carbamoyl-3,3-diphenylpropyl)ethyldimethylammonium bromide |
| Chemical Name Translation |
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信息真实价格透明
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- A new anticholinergic drug. The new drug was superior to 0.6 mg. of atropine sulfate orally in its effects on gastric secretion and on gastric motility.
相关文献及参考
- [2]. SCHWARTZ IR, et al. The effect of ambutonium bromide, a new anticholinergic agent in ulcer therapy. Am J Gastroenterol. 1960 Jun;33:704-17.
- Attwood, D., et al.: J. Pharmacy Pharmacol., 28, 407 (1976),
- Kuhnert-Brandstaetter, M., et al.: Scientia Pharmaceutica, 46, 180 (1978),
- [1]. Southgate PJ. Central and peripheral actions of the acetylcholine antagonist, ambutonium bromide. Arch Int Pharmacodyn Ther. 1972 Apr;196(2):376-82.
- [1]. Southgate PJ. Central and peripheral actions of the acetylcholine antagonist, ambutonium bromide. Arch Int Pharmacodyn Ther. 1972 Apr;196(2):376-82.
- [2]. SCHWARTZ IR, et al. The effect of ambutonium bromide, a new anticholinergic agent in ulcer therapy. Am J Gastroenterol. 1960 Jun;33:704-17.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 24302 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 103,100,1955
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