Propiocaine Hydrochloride 3-(哌啶-1-基)-1-(4-丙氧基苯基)丙-1-酮盐酸盐

CAS 1155-49-3 MFCD01695012

化学结构图

1155-49-3
SMILES: CCCOc1ccc(C(=O)CCN2CCCCC2)cc1.Cl

化学属性

Mol. FormulaC17H26ClNO2
Mol. Weight311.85

别名和识别编码

Chemical NamePropiocaine Hydrochloride
CAS Number1155-49-3
Synonym 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-(Piperidin-1-yl)-1-(4-propoxyphenyl)propan-1-one hydrochloride {} {} {} {} {} {} {} {} {} {} {} {} {
Chemical Name Translation3-(哌啶-1-基)-1-(4-丙氧基苯基)丙-1-酮盐酸盐
Wiswesser Line NotationT6NTJ A2VR DO3 &GH
PubChem Substance ID70863
InChIInChI=1S/C17H25NO2.ClH/c1-2-14-20-16-8-6-15(7-9-16)17(19)10-13-18-11-4-3-5-12-18;/h6-9H,2-5,10-14H2,1H3;1H
Canonical SMILESCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
MDL NumberMFCD01695012
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分类

  • Aromatocs
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A local anesthetic

相关文献及参考

  • Stephenson, G., et al.: J. Pharm. Sci., 87, 536

安全信息

RTECSUH4420000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   31,21,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,559,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Behavioral - irritability
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 115,419,1955

Storage condition

系列性分类

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