N-(Azepan-1-Ylcarbamoyl)-4-Methylbenzenesulfonamide N-(氮杂卓-1-基氨基甲酰基)-4-甲基苯磺酰胺
CAS 1156-19-0 MFCD00083504
化学结构图
SMILES: Cc1ccc(S(=O)(=O)NC(=O)NN2CCCCCC2)cc1
化学属性
| Mol. Formula | C14H21N3O3S |
|---|---|
| Mol. Weight | 311 |
别名和识别编码
| Chemical Name | N-(Azepan-1-Ylcarbamoyl)-4-Methylbenzenesulfonamide |
|---|---|
| CAS Number | 1156-19-0 |
| Synonym | U-17835 1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)urea Benzenesulfonamide, ######## 4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide n,((hexahydro-1h-azepin-1-yl)amino)carbonyl)-4-methyl-benzenesulfonamid Tolazamide SALOR-INT L254916-1EA norglycin 1-(Hexahydro-1H-azepin-1-yl)-3-(p-toluenesulfonyl)urea n-(p-toluenesulfonyl)-n’-hexamethyleniminourea TOLAZAMIDE tolazolamide n-(((hexahydro-1h-azepin-1-yl)-amino)carbonyl)-4-methyl-benzenesulfonamid 1-[HEXAHYDRO-1H-AZEPIN-1-YL]-3-[P-TOLUENESULFONYL]UREA 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea n-[[(hexahydro-1h-azepin-1-yl)-amino]carbonyl]-4-methylbenzenesulfonamide nsc-70762 LABOTEST-BB LT00772329 tolanase nci-c03327 妥拉磺脲 1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)-ure diabewas N-[[(HEXAHYDRO-1H-AZEPINYL)AMINO]CARBONYL]-4-METHYLBENZENESULFONAMIDE |
| MDL Number | MFCD00083504 |
| PubChem Substance ID | 24277741 |
| EC Number | 214-588-3 |
| Chemical Name Translation | N-(氮杂卓-1-基氨基甲酰基)-4-甲基苯磺酰胺 |
| Wiswesser Line Notation | T7NTJ AMVMSWR D1 |
| Beilstein Registry Number | 1323565 |
| LabNetwork Molecule ID | LN00197499 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Johnson & Johnson, Monovalent Ion Channels, Potassium Channel Modulators, T, Voltage-gated Ion Channels
产品应用
- Tolazamide
相关文献及参考
- Welling, et al.: J. Pharma. Sci., 71, 1259 (1982),
安全信息
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,1521,1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 256 mg/kg/3W-I TOXIC EFFECTS : Liver - jaundice, other or unclassified Liver - liver function tests impaired REFERENCE : GASTAB Gastroenterology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1943- Volume(issue)/page/year: 89,192,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,1521,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,511,1982
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 4 mmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 368,59,1996
其他信息
- Sigma Aldrich:1156-19-0(sigmaaldrich)
- MOL 文件:1156-19-0.mol
京ICP备2020036287号