Chlorthenoxazine

CAS 132-89-8 MFCD00012095

化学结构图

132-89-8
SMILES: O=C1NC(CCCl)Oc2ccccc21

化学属性

Mol. FormulaC10H10ClNO2
Mol. Weight211.66

别名和识别编码

Chemical Namechlorthenoxazine
Wiswesser Line NotationT66 BVM EO DHJ D2G
Synonym 2-(2-Chloroethyl)-2,3-dihydro-4-oxo-1,3-benzoxazine 2-(2-Chloroethyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one 2-(2-Chloroethyl)-3-aza-4-chromanone 2-(2-chloroethyl)-2,3-dihydro-(4H)-1,3-benzoxazin-4-one 2-(beta-Chloroethyl)-2,3-dihydro-4-oxo(benzo-1,3-oxazine) 4-Oxo-2-(beta-chloroethyl)-2,3-dihydrobenzo-1,3-oxazine AP 67 Ap-67 Apirazin Chlorethylbenzmethoxazone Chlorthenoxazin Chlorthenoxazine Reumagrip Valmorin Valtorin chlortenoxazin chlorthenoxazin chlorthenoxazin hydrochloride
CAS Number132-89-8
Beilstein Registry Number0170863
PubChem Substance ID8602
InChIInChI=1S/C10H10ClNO2/c11-6-5-9-12-10(13)7-3-1-2-4-8(7)14-9/h1-4,9H,5-6H2,(H,12,13)
LabNetwork Molecule IDLN03246288
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安全信息

RTECSDM3675000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1702 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,884,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,651,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11155 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,884,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 730 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   1,36,1960

系列性分类

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