Diethylproion Hydrochloride 盐酸安非拉酮(精神类药品，不能销售)

CAS 134-80-5 MFCD00058013

化学结构图

134-80-5
SMILES: CCN(CC)C(C)C(=O)c1ccccc1.Cl

化学属性

Mol. FormulaC13H19NO.ClH
Mol. Weight241.79

别名和识别编码

Chemical NameDiethylproion Hydrochloride
CAS Number134-80-5
Synonym Amphepramonum hydrochloride ?-Benzoyltriethylammonium Chloride Anorex Tenuate-Dospan Tenuate hydrochloride alpha-Benzoyltriethylammonium chloride Regenon hydrochloride 2-(Diethylamino)-1-phenyl-1-propanone Hydrochloride Diethylpropion hydrochloride; 2-(Diethylamino)-1-phenyl-1-propanone hydrochloride Amfepramon hydrochloride 2-Diethylaminopropiophenone hydrochloride Diethylpropione hydrochloride 1-Phenyl-2-diethylaminopropanone-1 hydrochloride 1-Propanone, 2-(diethylamino)-1-phenyl-, hydrochloride Dobesin Moderatan Tenuate Tenapil 2-(Diethylamino)propiophenone Hydrochloride alpha-Benzoyltriethylamine hydrochloride Amfepramon Hydrochloride Diethylpropion hydrochloride 1-Phenyl-2-diethylamino-1-propanone hydrochloride
EC Number205-156-5
Wiswesser Line Notation2N2&Y1&VR &GH
PubChem Substance ID91442
InChIInChI=1S/C13H19NO.ClH/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12;/h6-11H,4-5H2,1-3H3;1H
Chemical Name Translation盐酸安非拉酮(精神类药品，不能销售)
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Controlled substance (stimulant). Anorexic.

相关文献及参考

  • Cahen, et al.: Therapie, 17, 373 (1962),
  • Abramson, R., et al.: J. Clin. Psychiatry, 41, 234 (1980),

安全信息

RTECSUH0360000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - excitement
   Skin and Appendages - hair
REFERENCE :
   APSXAS Acta Pharmaceutica Suecica.  (Apotekarsocieteten-Farmacevtiska
   Foereningen, Box 1136, S-111, 81 Stockholm, Sweden)  V.1-    1964-
   Volume(issue)/page/year: 4,37,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 139 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   17,121,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 385 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 17,373,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue

系列性分类

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