N-Phenyl-2-naphthylamine N-苯基-2-萘胺

CAS 135-88-6 MFCD00004052

化学结构图

135-88-6
SMILES: c1ccc(Nc2ccc3ccccc3c2)cc1

化学属性

Mol. FormulaC16H13N
Mol. Weight219
Boiling Point395-395.5
Melting Point105-108
Density1.24
Solubility不溶. <0.1 G/100 ML AT 19 ºC
Stability对光敏感

别名和识别编码

Chemical NameN-Phenyl-2-naphthylamine
Synonym 2-(Phenylamino)naphthalene 2-ANILINONAPHTHALENE 2-Naphthalenamine, N-phenyl- 2-Naphthylamine, N-phenyl- 2-anilinonaphthalene AK 1 (stabilizer) Aceto PBN Antioxidant 116 Antioxidant D Antioxidant PBN Fenyl-beta-naftylamin N-(2-Naphthyl)aniline, 2-Anilinonaphthalene N-(2-萘基)苯胺 N-2-NAPHTHYLANILINE N-Fenyl-2-aminonaftalen N-P N-PHENYL-BETA-NAPHTHYLAMINE N-Phenyl-2-naphthylamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00004052
CAS Number135-88-6
PubChem Substance ID8679
Beilstein Registry Number2211188
EC Number205-223-9
Reaxys-RN2211188
Chemical Name TranslationN-苯基-2-萘胺
Wiswesser Line NotationL66J CMR
LabNetwork Molecule IDLN00242051
InChIInChI=1S/C16H13N/c1-2-8-15(9-3-1)17-16-11-10-13-6-4-5-7-14(13)12-16/h1-12,17H
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分类

  • {uni_hamburg} no charge; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; 1fragment
  • {SNA} Amines, Building Blocks, C15 to C19, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks

产品应用

  • 检验氯酸盐。有机合成。染料中间体。用作橡胶抗氧剂、润滑剂、聚合抑制剂 。

相关文献及参考

  • Short: II/3
  • Short: III/5b
  • Short:
  • Beilstein: 12,IV,3128
  • Short: IV/1a

安全信息

GHS Symbol
WGK Germany2
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H351 Suspected of causing cancer 怀疑致癌
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSQM4550000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P352
  • P302+P352+P333+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P318
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P333+P313
  • P333+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word
Safety Statements
Hazard Codes
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R53 May cause long-term adverse effects in the aquatic environment 对水生环境有长期的有害作用
  • R51 Toxic to aquatic organisms 对水生生物有毒
  • R51/53
Packing GroupIII
UN Number
Hazard Class9
Storage condition 密封阴凉干燥避光保存。
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 135 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17280 mg/kg/9W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   44,3098,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 208 gm/kg/97W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   SYSWAE Shiyan Shengwu Xuebao.  Journal of Experimental Biology.  (China
   International Book Trading Corp., POB 2820, Beijing

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 264 gm/kg/99W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   SYSWAE Shiyan Shengwu Xuebao.  Journal of Experimental Biology.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1953-    Suspended

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1450 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   31(1-3),183,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8730 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   31(1-3),183,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8700 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Liver - other changes
REFERENCE :
   TJSGA8 Tijdschrift Voor Sociale Geneeskunde.  (B.V. Uitgeversmaatschappij.
   Reflex, Mathenesserlaan 310, Rotterdam 3003, Netherlands)  V.1-    1923-
   Volume(issue)/page/year: 53,415,1975

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 23100 ug/L
REFERENCE :
   ITCSAF In Vitro.  (Rockville, MD)  V.1-20, 1965-85.  For publisher
   information, see ICDBEO.  Volume(issue)/page/year: 17,719,1981

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 360 mg/kg/18D
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 23(9),57,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 pph
REFERENCE :
   CYGEDX Cytology and Genetics (English Translation).  Translation of TGANAK.
   (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011)  V.8-    1974-
   Volume(issue)/page/year: 21(6),29,1987

其他信息

  • 用途一:适用于天然橡胶、合成橡胶和胶乳
  • MSDS 信息:N-苯基-2-萘胺(135-88-6).msds
  • TCI Shanghai:N-苯基-2-萘胺 N-Phenyl-2-naphthylamine,>;97.0%(T)(135-88-6)
  • 溶于乙醇、、苯、丙酮、乙酸和乙醚,不溶于水。。有毒。对皮肤有刺激性。
  • 方法一:2-萘酚与苯胺在苯胺盐酸盐的催化下,于250℃进行缩合而得。将2-萘酚与苯加入缩合锅内熔化,投入苯胺盐酸盐进行缩合。反应结束后,用碳酸钠中和。蒸出过量的苯胺,再在真空下脱水干燥,经切片、打粉、包装即得防老剂丁。原料消耗(kg/t)2-萘酚(98.5%) 660苯胺(99.2%) 425
  • 用途二:该品是天然橡胶、二烯类合成橡胶、氯丁橡胶及基胶乳用通用型防老剂。对热、氧、屈挠及一般老化有良好的防护作用,并稍优于防老剂甲。对有害金属有抑制作用,但较防老剂甲弱。若与防老剂4010或4010NA并用,则抗热、氧、屈挠龟裂,以及抗臭氧性均有显著提高。本品对天然胶、丁腈胶、丁苯胶的硫化速度无甚影响,对氯丁胶则稍有迟延作用。本品在干胶中容易分解,亦容易分散于水中。本品在橡胶中的溶解度约1.5%,用量不超过1份不会发生喷霜。该品有污染性,在日光下渐变为灰黑色,故不适用于白色或浅色制品。主要用于制造轮胎、胶管、胶带、胶辊、胶鞋、电线电缆绝缘层等工业制品。防老剂丁还可作各种合成橡胶后处理和贮存时的稳定剂,可用作聚甲醛的抗热防老剂。该品对皮肤有一定的刺激性。
  • MOL 文件:135-88-6.mol
  • 上游原料:盐酸 --> 氨基苯 --> 2-羟基萘
  • Sigma Aldrich:135-88-6(sigmaaldrich)
  • 外观性质:淡灰色针状结晶或粉末。
  • N-苯基-2-萘胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0198 N-苯基-2-萘胺 N-Phenyl-2-naphthylamine 500G 650元 2014/06/02 P0198 N-苯基-2-萘胺 N-Phenyl-2-naphthylamine 25G 90元
  • 图谱信息:N-苯基-2-萘胺(135-88-6)核磁图( 13 CNMR) N-苯基-2-萘胺(135-88-6)红外图谱(IR2) N-苯基-2-萘胺(135-88-6)核磁图( 1 HNMR) N-苯基-2-萘胺(135-88-6)红外图谱(IR3) N-苯基-2-萘胺(135-88-6)红外图谱(IR1) N-苯基-2-萘胺(135-88-6)质谱(MS)
  • 用途三:检验氯酸盐。有机合成。染料中间体。用作橡胶抗氧剂、润滑剂、聚合抑制剂 。

系列性分类


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