Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1) N-月桂酰肌氨酸钠

CAS 137-16-6 MFCD00042728

化学结构图

137-16-6
SMILES: CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+]

化学属性

Mol. FormulaC15H28NNaO3
Mol. Weight293.38
Density1.033 g/mL at 20 °C
SolubilitySoluble in water (1 M) at 20 °C.
Stability对湿度敏感
Melting Point46 °C

别名和识别编码

Chemical NameGlycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
Synonym Lauroylsarcosine (sodium) {LY} Lauroylsarcosine (sodium) {} {LY} Lauroylsarcosine (sodium) {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {}
CAS Number137-16-6
PubChem Substance ID87571989
EC Number205-281-5
Beilstein Registry Number5322974
MDL NumberMFCD00042728
Reaxys-RN5322974
Merck Number4368
Chemical Name TranslationN-月桂酰肌氨酸钠
LabNetwork Molecule IDLN00227114
Canonical SMILESO=C(O[Na])CN(C)C(CCCCCCCCCCC)=O
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分类

  • {SNA} Anionic Detergents, Biochemicals and Reagents, Cell Lysis Reagents, Detergents, Detergents A to M, Detergents by Applications, Electrophoresis Chro
  • {SNA} Anionic Detergents, Biochemicals and Reagents, DNA和RNA纯化, Detergents, Detergents A to M, Detergents

产品应用

  • 阴离子表面活性剂。可用于RNA、DNA离析，作为细胞纯化中的溶解剂，从人血清中分离DNA时的添加剂，还可以通过添加该产品增加豆科植物根瘤菌的固氮能力，在免疫化学方面也有许多应用。

相关文献及参考

  • Merck: 14,4368 Beilstein: 4,IV,2387
  • Schmookler, R. J., Properties of the polyoma virus transcription complex obtained from mouse nuclei. Virology 57 , 122, (1974) 摘要
  • D.E. Mahoney, Lysis of Clostridium perfringens for the rapid extraction of plasmids. Appl. Environ. Microbiol. 51 , 521, (1986)
  • P. Gariglio, Useful for rupturing eukaryote cells in transcription studies. FEBS Lett. 44 , 330, (1974) 摘要
  • Wroblewski, W., Solubilization of Spiroplasma citri cell membrane proteins with the anionic detergent sodium lauroyl-sarcosinate (Sarkosyl). Biochimie 60 , 389, (1978) 摘要
  • Merck: 14,4368

安全信息

GHS Symbol
WGK Germany1
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H330 Fatal if inhaled 吸入致命
Personal Protective Equipment Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P352+P332+P313+P362+P364
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
RTECSMC0598960
UN Number 2811
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时，佩带适当的呼吸器；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes 6.1 T
Risk Statements
  • R23 Toxic by inhalation 吸入有毒
  • R38 Irritating to skin 刺激皮肤
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
Packing GroupII
Hazard Class6.1
Storage condition 2-8°C {LY} 2-8°C Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°

其他信息

  • Lauroylsarcosine, sodium salt is an ionic detergent used to purify membrane proteins. Lauroylsarcosine, sodium salt also decreases transcription efficiency. Lauroylsarcosine, Sodium Salt is an inhibitor of HXK.

系列性分类

  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Detergents A to M - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Anionic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. BioUltra Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Anionic Detergents - Detergents
  4. Other Anionic Detergents - Anionic Detergents
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. DNA & RNA Purification - Molecular Biology
  4. Reagents - DNA & RNA Purification
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Glycine Derivatives - Unnatural Amino Acid Derivatives
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Signal Transduction Research Tools - Cell Signaling and Neuroscience
  5. Cell Lysis Reagents - Signal Transduction Research Tools
  6. Detergents - Cell Lysis Reagents
  1. Functional Group 官能团索引
  2. carboxylic acid salt

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