Methanesulfonanilide,3'-(1-hydroxy-2-(methylamino)ethyl)-,monomethanesulfonate (salt)

CAS 1421-68-7 MFCD01715354

化学结构图

1421-68-7
SMILES: CNCC(O)c1cccc(NS(C)(=O)=O)c1.CS(=O)(=O)O

化学属性

Mol. FormulaC10H16N2O3S.CH4O3S
Mol. Weight340.45

别名和识别编码

Chemical NameMethanesulfonanilide,3'-(1-hydroxy-2-(methylamino)ethyl)-,monomethanesulfonate (salt)
Wiswesser Line NotationWS1&MR CYOSWO1& 1M1
Synonym 3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide Amidephrine monomethanesulfonate Amidefrine mesylate Amidephrine mesylate 3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide methanesulfonate Dricol
CAS Number1421-68-7
PubChem Substance ID15009
InChIInChI=1S/C10H16N2O3S.CH4O3S/c1-11-7-10(13)8-4-3-5-9(6-8)12-16(2,14)15;1-5(2,3)4/h3-6,10-13H,7H2,1-2H3;1H3,(H,2,3,4)
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安全信息

Warnings 危化品目录(2015) 危险化学品
RTECSPB0870200
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJNEAQ International Journal of Neuropharmacology.  (New York, NY)  V.1-8,
   1962-69.  For publisher information, see NEPHBW.  Volume(issue)/page/year:
   4,219,1965

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TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,589,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,589,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1990 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJNEAQ International Journal of Neuropharmacology.  (New York, NY)  V.1-8,
   1962-69.  For publisher information, see NEPHBW.  Volume(issue)/page/year:
   4

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