Lonetil M3

CAS 1897-96-7 MFCD N/A

化学结构图

1897-96-7
SMILES: CCOc1ccc(-n2c(C)nc3ccccc3c2=O)cc1

化学属性

Mol. FormulaC17H16N2O2
Mol. Weight280.35

别名和识别编码

Chemical NameLonetil M3
Chemicalbook IDCB11326300
Wiswesser Line NotationT66 BVN ENJ CR DO2& D1
Synonym Lonetil 3-(p-Ethoxyphenyl)-2-methyl-4(3H)-quinazolinone B 146 Lonethyl 4(3H)-Quinazolinone, 3-(4-ethoxyphenyl)-2-methyl- 2-Methyl-3-(4'-aethoxyphenyl)chinazolinone(4)
CAS Number1897-96-7
Beilstein Registry Number0255500
InChIKeyJKWBQCHTVBSJDC-UHFFFAOYSA-N
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安全信息

RTECSVA3376000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - muscle contraction or spasticity
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,626,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 1,379,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3420 mg/kg
TOXIC EFFECTS :
   Immunological Including Allergic - other immediate (humoral): urticaria,
   allergic rhinitis, serum sickness
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 1,379,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issu

系列性分类


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