N-Cbz-L-Leucine N-Cbz-L-亮氨酸

CAS 2018-66-8 MFCD00026494

化学结构图

2018-66-8
SMILES: CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O

化学属性

Mol. FormulaC14H19NO4
Mol. Weight265.31
Density1.0
Refractive indexn20/D 1.512(lit.)
Flash Point>110°(230°F)
TSCANo
Appearance viscous liquid
Boiling Point408.52 °C at 760 mmHg

别名和识别编码

Chemical NameN-Cbz-L-Leucine
Synonym N-[(Phenylmethoxy)carbonyl]-L-leucine {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-[(Phenylmethoxy)carbonyl]-L-leucine {} {} {} {} {} {} {} {} {} {} {
Beilstein Registry Number1253861
CAS Number2018-66-8
EC Number217-960-3
MDL NumberMFCD00026494
PubChem Substance ID87565818
Reaxys-RN1253861
Chemical Name TranslationN-Cbz-L-亮氨酸
InChIKeyUSPFMEKVPDBMCG-LBPRGKRZSA-N
LabNetwork Molecule IDLN00009492
Canonical SMILESCC(C)C[C@@H](C(O)=O)NC(OCC1=CC=CC=C1)=O
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Amino Acid Derivatives, Chemical Biology, Chemical Synthesis, Leucine, Peptide Chemistry
  • {SNA} Amino Acid Derivatives, Chemical Biology, Chemical Synthesis, Leucine, Peptide Chemistry
  • {SNA} Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Leucine, Peptide Chemistry

产品应用

  • 用于生化试剂，缩宫素等多肽合成。

相关文献及参考

  • Beilstein: 6,III,1503

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves
GHS Symbol
Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
  • H226 Flammable liquid and vapour 易燃液体和蒸气
Hazard Codes 3 Xn
Precautionary statements
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Signal word Warning
RTECSOH2921000
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Risk Statements
  • R10 Flammable 易燃
  • R19 May form explosive peroxides 可能生成易爆的过氧化物质
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
UN Number 1993
Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Packing GroupIII 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 68,696,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 280 mg/kg
SEX/DURATION            : female 28 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 68,696,1979

其他信息

  • Sigma Aldrich:2018-66-8(sigmaaldrich)
  • 外观性质:无色或浅黄色油状物。密度:1.00 折射率:1.512闪点:85°
  • Acros Organics:N-羧基-L-亮氨酸 N-Carbobenzyloxy-L-leucine, 95%(2018-66-8)
  • 图谱信息:N-苄氧羰基-L-亮氨酸(2018-66-8)质谱(MS) N-苄氧羰基-L-亮氨酸(2018-66-8)红外图谱(IR1) N-苄氧羰基-L-亮氨酸(2018-66-8)红外图谱(IR2) N-苄氧羰基-L-亮氨酸(2018-66-8)Raman光谱
  • 比旋光度:-17 ° (c=2, ethanol)
  • 用途一:用于生化试剂，缩宫素等多肽合成。
  • N-苄氧羰基-L-亮氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0739 N-苄氧羰基-L-亮氨酸 N-Carbobenzoxy-L-leucine 5G 112元 2014/06/02 C0739 N-苄氧羰基-L-亮氨酸 N-Carbobenzoxy-L-leucine 25G 453元 2010/06/21 275970250 N-苄氧羰基-L-亮氨酸 N-Carbobenzyloxy-L-leucine 95% 25 GR 1385元
  • TCI Shanghai:N-苄氧羰基-L-亮氨酸 N-Carbobenzoxy-L-leucine,>;96.0%(T)(2018-66-8)
  • MOL 文件:2018-66-8.mol
  • Alfa Aesar:N-苄氧羰基-L-亮氨酸,98+%(drywt.),maycont.uptoca5%solvent N-Benzyloxycarbonyl-L-leucine, 98+% (dry wt.), may cont. up to ca 5% solvent(2018-66-8)
  • MSDS 信息:Z-Leu-OH(2018-66-8).msds

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Amino Acid Derivatives 氨基酸及其衍生物
  5. Leucine - Amino Acid Derivatives
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Amino Acid Derivatives 氨基酸及其衍生物
  5. Leucine - Amino Acid Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. Cbz-amino Acids
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Protected & Labeled Amino Acids

相关产品推荐