Guanoxan

CAS 2165-19-7 MFCD00865888

化学结构图

2165-19-7
SMILES: N=C(N)NCC1COc2ccccc2O1

化学属性

Mol. FormulaC10H13N3O2
Mol. Weight207.26

别名和识别编码

Chemical NameGuanidine, (1,4-benzodioxan-2-ylmethyl)-
CAS Number2165-19-7
Synonym ((2,3-Dihydro-1,4-benzodioxin-2-yl)methyl)guanidine (1,4-Benzodioxan-2-ylmethyl)guanidine 2-(Guanidinomethyl)-1,4-benzodioxan Guanidine, ((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)- Guanoxan Guanoxane Guanoxon N-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]guanidine guanoxan
Chemical Name Translation
Beilstein Registry Number1251616
PubChem Substance ID16564
InChIInChI=1S/C10H13N3O2/c11-10(12)13-5-7-6-14-8-3-1-2-4-9(8)15-7/h1-4,7H,5-6H2,(H4,11,12,13)
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Guanoxan is a sympatholytic drug related to Guanethidine (G815000). Guanoxan is used in the treatment of hypertension.

相关文献及参考

  • Jack, D.B. et al.: Xenobiotica, 2, 35 (1972); Jack, D.B. et al.: J. Pharm. Pharmacol., 23, 222S (1971); Bueno, J.R. et al.: J. Pharm. Pharmacol., 20, 396 (1968);

安全信息

RTECSME8510200 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 208 mg/kg/1Y
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,296,1969

系列性分类

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